We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Front Cover: De Novo Design of Selective Quadruplex–Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot‐Spot (Chem. Eur. J. 20/2021).
- Authors
Díaz‐Casado, Laura; Serrano‐Chacón, Israel; Montalvillo‐Jiménez, Laura; Corzana, Francisco; Bastida, Agatha; Santana, Andrés G.; González, Carlos; Asensio, Juan Luis
- Abstract
Keywords: NMR structures; nucleic acids ligands; pharmacophores; quadruplex-duplex junctions; selective molecular recognition EN NMR structures nucleic acids ligands pharmacophores quadruplex-duplex junctions selective molecular recognition 6101 6101 1 04/09/21 20210407 NES 210407 B The structural motif defined by a G-quadruplex DNA b juxtaposed to duplex regions has been identified as a hot-spot for molecular recognition, and selectively targeted by a family of benzylamine-containing derivatives. Front Cover: De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot (Chem. Eur. J. 20/2021) NMR structures, nucleic acids ligands, pharmacophores, quadruplex-duplex junctions, selective molecular recognition.
- Subjects
LIGANDS (Chemistry); MOLECULAR recognition; NUCLEIC acids
- Publication
Chemistry - A European Journal, 2021, Vol 27, Issue 20, p6101
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.202100455