We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
MURRAY VALLEY ENCEPHALITIS VIRUS: PREPARATION OF AN INFECTIVE "RIBONUCLEIC ACID" FRACTION.
- Authors
Anderson, S. G.; Ada, G. L.
- Abstract
Crude suspensions of Murray Valley encephalitis virus, when treated with concentrated phenol, yielded an infective product; this has been designated "RNA". Both virus and "RNA" were titrated on the chorioallantoic membrane of 12-day chick embryos. The embryos died in three days. In appropriate diluents both virus and "RNA" lost 99 p.c. of their infectivity after 30 minutes at 48° C. "RNA" was inactivated by ribonuclease, normal rabbit serum, and extracts of spleen and lung. Extracts of mouse brain and liver protected the "RNA" against inactivation of each of these agents.
- Subjects
VIRUSES; RNA; PHENOLS; EMBRYOS; SERUM; SPLEEN; LUNGS
- Publication
Australian Journal of Experimental Biology & Medical Science, 1959, Vol 37, Issue 4, p353
- ISSN
0004-945X
- Publication type
Article
- DOI
10.1038/icb.1959.37