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- Title
Permeability and wettability of bioresorbable nanofiber nonwoven membranes.
- Authors
Großmann, Swen; Oldenburg, Jan; Ott, Robert; Stiehm, Michael; Schmitz, Klaus-Peter; Siewert, Stefan; Illner, Sabine; Grabow, Niels
- Abstract
Nanofiber nonwoven membranes produced by electrospinning provide the possibility to adjust mechanical material parameters as well as simultaneously the biologically relevant properties - a fundamental aspect in developing new implants and medical devices. Wettability and permeability are also of great importance, as they have a decisive influence on the release of drugs, cell attachment, degradability and finally the nutrient supply of the surrounding tissue. Within this work the wettability and permeability of several electrospun poly-L-lactide nonwovens, including different additives, were investigated and a correlation to membrane morphology was found. A potential modification of the permeability by the fluid viscosity was also investigated. The results form a fundamental building block in the development of permeable biodegradable implants and medical devices.
- Publication
Current Directions in Biomedical Engineering, 2020, Vol 6, Issue 3, p461
- ISSN
2364-5504
- Publication type
Article
- DOI
10.1515/cdbme-2020-3119