We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
舒芬太尼在小儿先天性心脏病手术麻醉中对血流动力学的影响.
- Authors
王小燕; 汪毅; 王钊; 夏阳; 刘源; 王俊玉
- Abstract
Objective To compare the effects of sufentanil and fentanyl on hemodynamics of pediatric patients undergoing congenital cardiac repair.Methods Sixty children scheduled for elective surgery of congenital cardiac defects was selected. Patients were randomly divided into two groups: sufentanil group(Group S,n=30) and fentanyl group(Group F,n=30) . Anesthesia was induced with midazolam 0.1~0.2 mg/kg , vecuronium 0.1 mg/kg and sufentanil 0.7 滋g/kg(in group S) / fentanyl 7 滋g/kg(in group F), and maintained with intermittent iv boluses of midazolam and vecuronium, inhale sevoflurane, and then pre-incision and pre-cardiopulmonary bypass(CPB) sufentanil 0.7 滋g/kg (in group S) /fentanyl7 滋g/kg(in group F) was injected intravenously again. The patients were mechanically ventilated after tracheal intubation. SBP,DBP, MAP and HR were recorded before anesthesia induction (T0),after anesthesia induction (T1),after tracheal intubation (T2),after skin incision (T3), after sternal saw (T4), the end of operation (T5).Operation duration, cardiopulmonary bypass time, aortic cross-clamping time and the dose of sufentanil and fentanyl were recorded. Results Compared with T0, SBP, DBP and MAP of patients in two groups decreased( <0.01), there was significant difference between two groups( <0.01),HR also decreased ( <0.01),whereas there was no significant difference between two groups ( <0.01);Compared with T0, SBP, DBP,MAP and HR decreased at T1 and T2 but there was no significant difference in group S. Compared with T0,SBP,DBP, MAP and HR at T1 and T2 but there was significant difference in group F. Conclusion Sufentanil can be safely used in children undergoing heart surgery,and has less changes in hemodynamics than equivalent dose of fentanyl.
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2013, Issue 2, p106
- ISSN
2095-610X
- Publication type
Article