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- Title
Non-Occlusive Mesenteric Ischemia in Children With Diabetic Ketoacidosis: Case Report and Review of Literature.
- Authors
Frontino, Giulio; Di Tonno, Raffaella; Castorani, Valeria; Rigamonti, Andrea; Morotti, Elisa; Sandullo, Federica; Scialabba, Francesco; Arrigoni, Francesca; Foglino, Riccardo; Dionisi, Benedetta; Ferri, Chiara Irene Carla; Zirpoli, Salvatore; Barera, Graziano; Meschi, Franco; Bonfanti, Riccardo
- Abstract
Introduction: Despite the use of technology, recurrent diabetic ketoacidosis (DKA) prevention remains an unmet need in children and adolescents with T1D and may be accompanied by life-threatening acute complications. We present a rare case of nonocclusive mesenteric ischemia (NOMI) with overt manifestation after DKA resolution and a discussion of recent literature addressing DKA-associated NOMI epidemiology and pathogenesis in children and adolescents. Case Presentation: A 13-year-old female with previously diagnosed T1D, was admitted at our emergency department with hypovolemic shock, DKA, hyperosmolar state and acute kidney injury (AKI). Mildly progressive abdominal pain persisted after DKA correction and after repeated ultrasound evaluations ultimately suspect for intestinal perforation, an intraoperative diagnosis of NOMI was made. Conclusion: The diagnosis of DKA-associated NOMI must be suspected in pediatric patients with DKA, persistent abdominal pain, and severe dehydration even after DKA resolution.
- Subjects
MESENTERIC ischemia; DIABETIC acidosis; ACUTE kidney failure; ABDOMINAL pain; LITERATURE reviews; INTESTINAL perforation
- Publication
Frontiers in Endocrinology, 2022, Vol 13, p1
- ISSN
1664-2392
- Publication type
Article
- DOI
10.3389/fendo.2022.900325