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Drosophila models of Alzheimer's amyloidosis: the challenge of dissecting the complex mechanisms of toxicity of amyloid-beta 42.
- Published in:
- 2008
- By:
- Publication type:
- journal article
Drosophila Models of Alzheimer's Amyloidosis: The Challenge of Dissecting the Complex Mechanisms of Toxicity of Amyloid-β 42.
- Published in:
- Journal of Alzheimer's Disease, 2008, v. 15, n. 4, p. 523, doi. 10.3233/JAD-2008-15402
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- Publication type:
- Article
Microtubule‐affinity regulating kinase family members distinctively affect tau phosphorylation and promote its toxicity in a Drosophila model.
- Published in:
- Genes to Cells, 2024, v. 29, n. 4, p. 337, doi. 10.1111/gtc.13101
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- Publication type:
- Article
Kinase activity of endosomal kinase LMTK1A regulates its cellular localization and interactions with cytoskeletons.
- Published in:
- Genes to Cells, 2016, v. 21, n. 10, p. 1080, doi. 10.1111/gtc.12404
- By:
- Publication type:
- Article
Inhibition of Sin3A/HDAC activity suppresses amyloid β-42 accumulation and toxicity through multiple mechanisms
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Disruption of mitochondrial transport promotes tau toxicity through Alzheimer's disease-related tau phosphorylation
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Studying mechanisms underlying Aβ42-induced tau toxicity in transgenic Drosophila models
- Published in:
- 2010
- By:
- Publication type:
- Abstract
DNA damage-activated Ser/Thr kinases phosphorylate tau and enhance tau-induced neurodegeneration
- Published in:
- 2010
- By:
- Publication type:
- Abstract
P1-028: Overexpression of neprilysin reduces Abeta42-induced neuron loss and intraneuronal Abeta42 deposits, but causes age-dependent axon pathology in drosophila
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P1-398: Characterization of the effect of protein contexts harboring polyglutamine stretch on CREB activity in Drosophila
- Published in:
- 2006
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- Publication type:
- Abstract
P1-006: Distinct accumulation properties of Aβ42 in the brain are associated with specific pathological phenotypes in Drosophila
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-398: Characterization of the effect of protein contexts harboring polyglutamine stretch on CREB activity in Drosophila
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-006: Distinct accumulation properties of Aβ42 in the brain are associated with specific pathological phenotypes in Drosophila
- Published in:
- 2006
- By:
- Publication type:
- Abstract
Quantitative and combinatory determination of in situ phosphorylation of tau and its FTDP-17 mutants.
- Published in:
- Scientific Reports, 2016, p. 33479, doi. 10.1038/srep33479
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- Publication type:
- Article
Regulation of Energy Stores and Feeding by Neuronal and Peripheral CREB Activity in Drosophila.
- Published in:
- PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008498
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- Publication type:
- Article
Mitochondrial Mislocalization Underlies Ab42-Induced Neuronal Dysfunction in a Drosophila Model of Alzheimer's Disease.
- Published in:
- PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008310
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- Publication type:
- Article
Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila.
- Published in:
- PLoS ONE, 2008, v. 3, n. 2, p. 1, doi. 10.1371/journal.pone.0001703
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- Publication type:
- Article
Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-69400-9
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- Publication type:
- Article
Structural Characterization and Protein Adsorption Property of Hydroxyapatite Particles Modified With Zinc Ions.
- Published in:
- Journal of the American Ceramic Society, 2007, v. 90, n. 2, p. 565, doi. 10.1111/j.1551-2916.2006.01396.x
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- Publication type:
- Article
SARS‐CoV‐2‐derived protein Orf9b enhances MARK2 activity via interaction with the autoinhibitory KA1 domain.
- Published in:
- FEBS Letters, 2024, v. 598, n. 19, p. 2385, doi. 10.1002/1873-3468.14975
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- Publication type:
- Article
Transgenic Drosophila models of Alzheimer’s disease and tauopathies.
- Published in:
- Brain Structure & Function, 2010, v. 214, n. 2/3, p. 245, doi. 10.1007/s00429-009-0234-4
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- Publication type:
- Article
5-Aminolevulinic acid bypasses mitochondrial complex I deficiency and corrects physiological dysfunctions in Drosophila.
- Published in:
- Human Molecular Genetics, 2023, v. 32, n. 16, p. 2611, doi. 10.1093/hmg/ddad092
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- Publication type:
- Article
Valproic Acid-Induced Anxiety and Depression Behaviors are Ameliorated in p39 Cdk5 Activator-Deficient Mice.
- Published in:
- Neurochemical Research, 2022, v. 47, n. 9, p. 2773, doi. 10.1007/s11064-022-03642-9
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- Publication type:
- Article
Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1.
- Published in:
- Journal of Biochemistry, 2021, v. 170, n. 6, p. 729, doi. 10.1093/jb/mvab094
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- Publication type:
- Article
Isoform-dependent subcellular localization of LMTK1A and LMTK1B and their roles in axon outgrowth and spine formation.
- Published in:
- Journal of Biochemistry, 2020, v. 168, n. 1, p. 23, doi. 10.1093/jb/mvaa019
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- Publication type:
- Article
Ca<sup>2+</sup>/calmodulin-dependent protein kinase II promotes neurodegeneration caused by tau phosphorylated at Ser262/356 in a transgenic Drosophila model of tauopathy.
- Published in:
- Journal of Biochemistry, 2017, v. 162, n. 5, p. 335, doi. 10.1093/jb/mvx038
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- Publication type:
- Article
Interaction of N-Terminal Acetyltransferase with the Cytoplasmic Domain of β-Amyloid Precursor Protein and Its Effect on Aβ Secretion.
- Published in:
- Journal of Biochemistry, 2005, v. 137, n. 2, p. 147, doi. 10.1093/jb/mvi014
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- Publication type:
- Article
Mark4 ablation attenuates pathological phenotypes in a mouse model of tauopathy.
- Published in:
- Brain Communications, 2024, v. 6, n. 3, p. 1, doi. 10.1093/braincomms/fcae136
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- Publication type:
- Article
Hippocampal hyperphosphorylated tau-induced deficiency is rescued by L-type calcium channel blockade.
- Published in:
- Brain Communications, 2024, v. 6, n. 2, p. 1, doi. 10.1093/braincomms/fcae096
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- Publication type:
- Article
Hyperactive and impulsive behaviors of LMTK1 knockout mice.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72304-z
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- Publication type:
- Article
Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo.
- Published in:
- Human Molecular Genetics, 2021, v. 30, n. 21, p. 1955, doi. 10.1093/hmg/ddab162
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- Publication type:
- Article
Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
- Published in:
- Human Molecular Genetics, 2019, v. 28, n. 18, p. 3062, doi. 10.1093/hmg/ddz120
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- Publication type:
- Article
The LMTK1-TBC1D9B-Rab11A Cascade Regulates Dendritic Spine Formation via Endosome Trafficking.
- Published in:
- Journal of Neuroscience, 2019, v. 39, n. 48, p. 9491, doi. 10.1523/JNEUROSCI.3209-18.2019
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- Publication type:
- Article
Loss of Axonal Mitochondria Promotes Tau-Mediated Neurodegeneration and Alzheimer's Disease--Related Tau Phosphorylation Via PAR-1.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002918
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- Publication type:
- Article
5‐Aminolevulinic acid and sodium ferrous citrate ameliorate muscle aging and extend healthspan in Drosophila.
- Published in:
- FEBS Open Bio, 2022, v. 12, n. 1, p. 295, doi. 10.1002/2211-5463.13338
- By:
- Publication type:
- Article
Tau Ser262 phosphorylation is critical for Aβ42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 15, p. 2947, doi. 10.1093/hmg/ddq200
- By:
- Publication type:
- Article
A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 10, p. 1930, doi. 10.1093/hmg/ddq068
- By:
- Publication type:
- Article
Neuron-Specific Phosphorylation of Alzheimer's β-Amyloid Precursor Protein by Cyclin-Dependent Kinase 5.
- Published in:
- Journal of Neurochemistry, 2000, v. 75, n. 3, p. 1085, doi. 10.1046/j.1471-4159.2000.0751085.x
- By:
- Publication type:
- Article
Diagnostic Utility and Safety of Non-Intubated Cryobiopsy Technique Using a Novel Ultrathin Cryoprobe in Addition to Conventional Biopsy Techniques for Peripheral Pulmonary Lesions.
- Published in:
- Respiration, 2023, v. 102, n. 7, p. 503, doi. 10.1159/000531010
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- Publication type:
- Article
Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in <italic>Drosophila</italic> models.
- Published in:
- Genome Medicine, 2018, v. 10, p. 1, doi. 10.1186/s13073-018-0530-9
- By:
- Publication type:
- Article
Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of ADRelated Phosphorylation and Aβ42-Induced Tau Toxicity.
- Published in:
- PLoS Genetics, 2016, v. 12, n. 3, p. 1, doi. 10.1371/journal.pgen.1005917
- By:
- Publication type:
- Article