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- Title
Effect and timing of non-surgical treatment prior to periodontal regeneration: a systematic review.
- Authors
Nibali, Luigi; Pelekos, George; Onabolu, Olanrewaju; Donos, Nikos
- Abstract
Objectives: The aim of this systematic review was to assess the study design and reporting of studies on periodontal regeneration, with respect to the effect of the provision of non-surgical periodontal therapy (NSPT) before surgery. Materials and Methods: A systematic search of the literature was conducted for studies on periodontal regeneration on Medline and EMBASE, complemented by a manual search. Initially, 3310 potentially eligible articles were identified. Results: A total of 293 studies were included in the review. Nearly 10 % of studies did not include NSPT in the study protocol before regenerative surgery, while 14 % of papers did not report this aspect. Seventy-six percent of studies reported that non-surgical subgingival debridement was performed before periodontal surgery (2 weeks to 6 months before surgery according to the different studies). However, no papers reported clinical and radiographic data before and after NSPT prior to periodontal surgery. Only 45 % of papers reported timing of reassessment following NSPT, prior to proceeding with regenerative surgery. Conclusions: This review highlights the lack of reporting information on non-surgical periodontal therapy prior to periodontal regenerative surgery, calling for a revision of the current clinical protocols and of the study designs of periodontal regenerative surgery studies. Clinical relevance: Periodontal regenerative surgery protocols should take into account the possible effects of non-surgical periodontal therapy in the clinical and radiographic healing of intrabony defects.
- Subjects
BONE regeneration; DENTAL radiography; REGENERATIVE medicine; PERIODONTITIS treatment; SYSTEMATIC reviews
- Publication
Clinical Oral Investigations, 2015, Vol 19, Issue 8, p1755
- ISSN
1432-6981
- Publication type
Article
- DOI
10.1007/s00784-015-1493-5