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- Title
Synthesis, Characterization, and Photophysical Properties of 2-Quinolone-Based Compounds.
- Authors
SAVRAN, Tahir
- Abstract
2-Quinolone (1,2-dihydroquinoline) and 1-aza coumarin derivatives are quinoline class pharmacophore structures known for their versatile bioactive and stable photophysical properties. In the present study, N-amino (2) and Nacetamido (3) derivatives of 2-quinolone-based 1-aza Coumarin-3-carboxylic acid were synthesized. Structure characterizations of the synthesized compounds were performed using 1H NMR, IR, 13C NMR spectral techniques. The synthesized compounds are thought to be precursor structures for the development of new bioactive agents because of their structural similarity. The photophysical sensitivities of compounds (2 and 3), which have the 1- Aza coumarin skeleton, in different solvents were examined by ultraviolet-visible (UV-Vis) absorption spectroscopy and fluorescence spectroscopy methods. In addition, the compounds synthesized in this study could serve as fluorophores, fluorescently active and bioactive new Schiff base sensors in different fluorescence studies.
- Subjects
QUINOLONE antibacterial agents; COUMARIN derivatives; NUCLEAR magnetic resonance; FLUOROPHORES; FLUORESCENCE spectroscopy
- Publication
Duzce University Journal of Science & Technology, 2024, Vol 12, Issue 2, p642
- ISSN
2148-2446
- Publication type
Article
- DOI
10.29130/dubited.1377215