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The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.11721
- By:
- Publication type:
- Article
Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23045-8
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- Publication type:
- Article
Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death.
- Published in:
- EMBO Journal, 2019, v. 38, n. 21, p. N.PAG, doi. 10.15252/embj.2019102718
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- Publication type:
- Article
The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.72103
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- Publication type:
- Article
Design principles for inflammasome inhibition by pyrin-only-proteins.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.81918
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- Publication type:
- Article
Reply.
- Published in:
- 2017
- By:
- Publication type:
- Letter
Association of Antibodies to Interferon-Inducible Protein-16 With Markers of More Severe Disease in Primary Sjögren's Syndrome.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC.
- Published in:
- Nature Communications, 2015, v. 6, n. 7, p. 7827, doi. 10.1038/ncomms8827
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- Publication type:
- Article
Filament assembly underpins the double-stranded DNA specificity of AIM2-like receptors.
- Published in:
- Nucleic Acids Research, 2023, v. 51, n. 6, p. 2574, doi. 10.1093/nar/gkad090
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- Publication type:
- Article
Allosteric coupling between Mn<sup>2+</sup> and dsDNA controls the catalytic efficiency and fidelity of cGAS.
- Published in:
- Nucleic Acids Research, 2020, v. 48, n. 8, p. 4435, doi. 10.1093/nar/gkaa084
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- Publication type:
- Article