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- Title
Evaluation Through the Optical Coherence Tomography Analysis of the Influence of Non-Alcoholic Fatty Liver Disease on the Gingival Inflammation in Periodontal Patients.
- Authors
Surlin, Petra; Didilescu, Andreea Cristiana; Lazar, Luminita; Arsenie, Cristian Cosmin; Camen, Adrian; Popescu, Dora Maria; Gheorghe, Dorin Nicolae; Osiac, Eugen; Rogoveanu, Ion
- Abstract
Purpose: The purpose of this ex vivo study is to exhibit the inflammatory changes that occur within the gingival tissue by using optical coherence tomography (OCT) in periodontal patients with non-alcoholic fatty liver disease (NAFLD) and if NAFLD could influence the local periodontal inflammation. Patients and Methods: Gingival tissue samples obtained from patients were divided into three groups – P (periodontitis), NAFLD+P (NAFLD+periodontitis) and H (healthy) groups - and were scanned using an OCT light beam, in order to perform a qualitative and quantitative analysis of images. The value of average pixel density has been associated with the degree of inflammation. Results: The highest average pixel density was found in patients from the H group, while the lowest value of average pixel density was recorded in gingival tissue samples collected from patients with NAFLD+P. The image assessments from NAFLD+P group delivered lower values of average pixel density than those of P group, suggesting a possible influence of this disease on the inflammatory tissular changes produced by periodontal disease. Conclusion: After comparing the OCT analysis results obtained for the three groups of patients, we can consider that NAFLD may be an aggravating factor for the inflammation of periodontal disease.
- Subjects
NON-alcoholic fatty liver disease; OPTICAL coherence tomography; GINGIVA; INFLAMMATION; IMAGE analysis
- Publication
Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2021, Vol 14, p2935
- ISSN
1178-7007
- Publication type
Article
- DOI
10.2147/DMSO.S310314