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- Title
Diabetic angiopathy and angiogenic defects.
- Authors
Ling Xu; Kanasaki, Keizo; Munehiro Kitada; Daisuke Koya
- Abstract
Diabetes is one of the most serious health problems in the world. A major complication of diabetes is blood vessel disease, termed angiopathy, which is characterized by abnormal angiogenesis. In this review, we focus on angiogenesis abnormalities in diabetic complications and discuss its benefits and drawbacks as a therapeutic target for diabetic vascular complications. Additionally, we discuss glucose metabolism defects that are associated with abnormal angiogenesis in atypical diabetic complications such as cancer.
- Subjects
DIABETES; VASCULAR diseases; GLUCOSE metabolism disorders; NEOVASCULARIZATION; CANCER; CARBOHYDRATE intolerance
- Publication
Fibrogenesis & Tissue Repair, 2012, Vol 5, Issue 1, p13
- ISSN
1755-1536
- Publication type
Article
- DOI
10.1186/1755-1536-5-13