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- Title
Evaluation of retinal functional changes after macular hole surgery using heavy brilliant blue G dye for internal limiting membrane staining: A prospective, single blind, randomized controlled trial.
- Authors
Kannan, Naresh; Chakrabarti, Anirban; Sen, Sagnik; Rajan, Renu; Kumar, Karthik; Baliga, Girish; Ramasamy, Kim; Kannan, Naresh Babu; Rajan, Renu P
- Abstract
<bold>Purpose: </bold>To evaluate retinal functional changes after idiopathic macular hole (MH) surgery using heavy brilliant blue G (hBBG) dye for internal limiting membrane (ILM) staining.<bold>Methods: </bold>Forty-four eyes with idiopathic MH were randomized into two groups - 24 eyes undergoing vitrectomy with ILM peeling using hBBG staining and 20 eyes without staining; anatomical and functional status (with microperimetry (MP)) at baseline and during postoperative follow-up were noted and compared.<bold>Results: </bold>All eyes had closure of MH postoperatively and overall baseline MP indices (average threshold, AT; foveal sensitivity, FS) improved significantly at 6 weeks and 6 months of follow-up. AT and FS showed significant improvement at 6 weeks and 6 months from baseline in both individual groups (P < 0.001). Intergroup comparison showed that there was no statistically significant difference in AT and FS values at any point of time (baseline, 6 weeks, 6 months) between staining and no-stain group. No eyes in our cohort had any unexplained visual loss.<bold>Conclusion: </bold>Functional parameters of macula improved significantly after successful MH surgery using hBBG for staining the ILM.
- Subjects
RETINAL disease diagnosis; RESEARCH; STAINS &; staining (Microscopy); RESEARCH methodology; RETROSPECTIVE studies; MEDICAL cooperation; EVALUATION research; AMINES; COMPARATIVE studies; RANDOMIZED controlled trials; VISUAL acuity; BLIND experiment; RETINAL diseases; BASAL lamina; LONGITUDINAL method
- Publication
Indian Journal of Ophthalmology, 2021, Vol 69, Issue 10, p2752
- ISSN
0301-4738
- Publication type
journal article
- DOI
10.4103/ijo.IJO_2816_20