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- Title
Hunter-Hurler Syndrome : Gel Filtration and Dialysis of Urinary Acid Mucopolysaccharides.
- Authors
CONSTANTOPOULOS, G.
- Abstract
PATIENTS with Hunter-Hurler syndrome, which is an inborn error of metabolism, have excessive deposition of acid mucopolysaccharides (AMPS) in various organs1,2, and large amounts of chondroitin sulphate B and/or heparitin sulphate are produced in the urine3. In contrast, normal people excrete a small amount of AMPS, chiefly in the form of chondroitin sulphate C and chondroitin sulphate A. The determination of urinary AMPS is being used extensively in the study and in the diagnosis of this disease and of its several genetic variants.
- Publication
Nature, 1968, Vol 220, Issue 5167, p583
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/220583b0