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PKC-θ exists in an oxidized inactive form in naive human T cells.
- Published in:
- European Journal of Immunology, 2013, v. 43, n. 6, p. 1659, doi. 10.1002/eji.201243140
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- Article
Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCθ in T lymphocytes.
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- EMBO Journal, 2005, v. 24, n. 22, p. 3869, doi. 10.1038/sj.emboj.7600856
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- Publication type:
- Article
Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-?, e and ?
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- EMBO Journal, 1998, v. 17, n. 14, p. 4046, doi. 10.1093/emboj/17.14.4046
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- Article
A MLR-Based Approach to Analyze Regulators of T Lymphocyte Activation In Vivo.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5337, doi. 10.3390/ijms23105337
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- Article
Determination of Protein-Protein Interactions of ICln by the Yeast Two-Hybrid System.
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- Cellular Physiology & Biochemistry (Karger AG), 2001, v. 11, n. 1, p. 55, doi. 10.1159/000047792
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- Publication type:
- Article
A role for the nuclear receptor NR2F6 in peritoneal B cell homeostasis.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.845235
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- Publication type:
- Article
Cerebral Malaria: Current Clinical and Immunological Aspects.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.863568
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- Publication type:
- Article
Translocation of PKCθ in T cells is mediated by a nonconventional, P13-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.
- Published in:
- Journal of Cell Biology, 2002, v. 157, n. 2, p. 253, doi. 10.1083/jcb.200201097
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- Publication type:
- Article
cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation.
- Published in:
- Scientific Reports, 2016, p. 20930, doi. 10.1038/srep20930
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- Publication type:
- Article
Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b.
- Published in:
- Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02311
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- Publication type:
- Article
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
- Published in:
- Journal of Molecular Cell Biology, 2013, v. 5, n. 6, p. 358, doi. 10.1093/jmcb/mjt017
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- Publication type:
- Article
Protein Kinase C θ Regulates the Phenotype of Murine CD4<sup>+</sup> Th17 Cells.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096401
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- Publication type:
- Article
LAMTOR2-Mediated Modulation of NGF/MAPK Activation Kinetics during Differentiation of PC12 Cells.
- Published in:
- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095863
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- Publication type:
- Article
The Role of the E3 Ligase Cbl-B in Murine Dendritic Cells.
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- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065178
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- Publication type:
- Article
PKCθ/β and CYLD Are Antagonistic Partners in the NFκB and NFAT Transactivation Pathways in Primary Mouse CD3<sup>+</sup> T Lymphocytes.
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- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053709
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- Publication type:
- Article
Adoptive Transfer of siRNA Cblb-Silenced CD8<sup>+</sup> T Lymphocytes Augments Tumor Vaccine Efficacy in a B16 Melanoma Model.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044295
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- Publication type:
- Article
PKN1 Exerts Neurodegenerative Effects in an In Vitro Model of Cerebellar Hypoxic–Ischemic Encephalopathy via Inhibition of AKT/GSK3β Signaling.
- Published in:
- Biomolecules (2218-273X), 2023, v. 13, n. 11, p. 1599, doi. 10.3390/biom13111599
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- Publication type:
- Article
Nuclear Receptors Regulate Intestinal Inflammation in the Context of IBD.
- Published in:
- Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01070
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- Publication type:
- Article
Emerging Next-Generation Target for Cancer Immunotherapy Research: The Orphan Nuclear Receptor NR2F6.
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- Cancers, 2021, v. 13, n. 11, p. 2600, doi. 10.3390/cancers13112600
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- Publication type:
- Article
The PKC gene module: molecular biosystematics to resolve its T cell functions.
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- Immunological Reviews, 2003, v. 192, n. 1, p. 64, doi. 10.1034/j.1600-065X.2003.00018.x
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- Publication type:
- Article
Differential requirements for ERK1/2 and P38 MAPK activation by thrombin in T cells. Role of P59Fyn and PKCε.
- Published in:
- Oncogene, 2001, v. 20, n. 16, p. 1964, doi. 10.1038/sj.onc.1204266
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- Publication type:
- Article
Protein kinase N1 critically regulates cerebellar development and long-term function.
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- 2018
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- Publication type:
- journal article
Protein kinase Cθ: the pleiotropic T-cell signalling intermediate.
- Published in:
- Biochemical Society Transactions, 2014, v. 42, n. 6, p. 1512, doi. 10.1042/BST20140179
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- Publication type:
- Article
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
- Published in:
- Nature, 2014, v. 507, n. 7493, p. 508, doi. 10.1038/nature12998
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- Publication type:
- Article
Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04004-2
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- Publication type:
- Article
Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02424-0
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- Publication type:
- Article
T cell‐intrinsic PKD3 fine‐tunes differentiation into CD8<sup>+</sup> central memory T cells and CD8 single positive thymocyte development.
- Published in:
- Immunology, 2024, v. 173, n. 1, p. 125, doi. 10.1111/imm.13804
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- Publication type:
- Article
Antigen-Specific Immunoregulatory Activity of a T Cell Receptor α Chain Generated by Expression PCR.
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- International Archives of Allergy & Immunology, 1995, v. 107, n. 1-3, p. 356, doi. 10.1159/000237031
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- Publication type:
- Article
Releasing the Brake: Targeting Cbl-b to Enhance Lymphocyte Effector Functions.
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- Clinical & Developmental Immunology, 2012, p. 1, doi. 10.1155/2012/692639
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- Publication type:
- Article
Reinforcement of cancer immunotherapy by adoptive transfer of cblb-deficient CD8<sup>+</sup> T cells combined with a DC vaccine.
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- Immunology & Cell Biology, 2012, v. 90, n. 1, p. 130, doi. 10.1038/icb.2011.11
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- Publication type:
- Article
AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling
- Published in:
- FEBS Letters, 2003, v. 541, n. 1-3, p. 155, doi. 10.1016/S0014-5793(03)00287-4
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- Publication type:
- Article
Critical role of protein kinase C α and calcium in growth factor induced activation of the Na<sup>+</sup>/H<sup>+</sup> exchanger NHE1
- Published in:
- FEBS Letters, 2002, v. 521, n. 1-3, p. 205, doi. 10.1016/S0014-5793(02)02867-3
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- Publication type:
- Article
Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4<sup>+</sup> T lymphocyte activation.
- Published in:
- Cell Communication & Signaling, 2019, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12964-019-0364-0
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- Publication type:
- Article
Role of PKCtheta in macrophage-mediated immune response to Salmonella typhimurium infection in mice.
- Published in:
- Cell Communication & Signaling, 2016, v. 14, p. 1, doi. 10.1186/s12964-016-0137-y
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- Publication type:
- Article
Novel Protein kinase C θ: Coronin 1A complex in T lymphocytes.
- Published in:
- Cell Communication & Signaling, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12964-015-0100-3
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- Article
Orphan nuclear receptor NR2F6 acts as an essential gatekeeper of Th17 CD4<sup>+</sup> T cell effector functions.
- Published in:
- Cell Communication & Signaling, 2014, v. 12, n. 1, p. 1, doi. 10.1186/1478-811X-12-38
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- Publication type:
- Article
Cbl-b Deficiency in Mice Results in Exacerbation of Acute and Chronic Stages of Allergic Asthma.
- Published in:
- Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00592
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- Publication type:
- Article
Involvement of distinct PKC gene products in T cell functions.
- Published in:
- Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00220
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- Publication type:
- Article
T cell expressed PKCθ demonstrates cell-type selective function.
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- European Journal of Immunology, 2000, v. 30, n. 12, p. 3645, doi. 10.1002/1521-4141(200012)30:12<3645::AID-IMMU3645>3.0.CO;2-#
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- Publication type:
- Article
Synergistic action of protein kinase C θ and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells.
- Published in:
- European Journal of Immunology, 1999, v. 29, n. 11, p. 3549, doi. 10.1002/(SICI)1521-4141(199911)29:11<3549::AID-IMMU3549>3.0.CO;2-Q
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- Publication type:
- Article
Protein kinase Cθ, a selective upstream regulator of JNK/SAPK and IL-2 promoter activation in Jurkat T cells.
- Published in:
- European Journal of Immunology, 1999, v. 29, n. 1, p. 132, doi. 10.1002/(SICI)1521-4141(199901)29:01<132::AID-IMMU132>3.0.CO;2-7
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- Publication type:
- Article
Activation of phosphatidylinositol-3-kinase in Jurkat T cells depends on the presence of the p56.
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- European Journal of Immunology, 1994, v. 24, n. 1, p. 234, doi. 10.1002/eji.1830240137
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- Publication type:
- Article
PKC-θ Modulates the Strength of T Cell Responses by Targeting Cbl-b for Ubiquitination and Degradation.
- Published in:
- Science Signaling, 2009, v. 2, n. 76, p. 1, doi. 10.1126/scisignal.2000046
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- Publication type:
- Article
Protein kinase C theta is dispensable for suppression mediated by CD25<sup>+</sup>CD4<sup>+</sup> regulatory T cells.
- Published in:
- PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0175463
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- Publication type:
- Article
Addressing the role of PKD3 in the T cell compartment with knockout mice.
- Published in:
- Cell Communication & Signaling, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12964-022-00864-w
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- Publication type:
- Article
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy.
- Published in:
- Cell Communication & Signaling, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12964-019-0454-z
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- Publication type:
- Article
Loss-of-function phenotype of a PKCθ<sup>T219A</sup> knockin mouse strain.
- Published in:
- Cell Communication & Signaling, 2019, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12964-019-0466-8
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- Publication type:
- Article