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- Title
早发型与成人型精神分裂症患者的认知功能.
- Authors
黄冰洁; 谢嘉恒; 蒲城城; 郭慧凝; 杨磊; 韩雪; 程章; 原岩波; 赵靖平; 王传跃; 陆峥; 杨甫德; 邓红; 石川; 于欣
- Abstract
Objective: To explore the characteristics of cognitive function in patients with early onset and adult onset schizophrenia. Methods: In this cross-seetional study, 546 patients with schizophrenia who met the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) were selected. Among them, 62 cases were defined as early onset schizophrenia (EOS, age of onset < 18years) and 175 patients were defined as adult onset schizophrenia (AOS, age of onset≥ 25years). Patients underwent clinical assessments with the Positive and Negative Symptom Scale (PANSS) and the Personal and Social Performance Scale (PSP), and comprehensive neuropsychological assessments. Results: The EOS patients got lower scores in motor function-PEGDOM T score [(26 ± 12)vs. (30 ± 11), P <0. 01], working memory- average T score of PASAT and WMSSP [(34 ± 12) vs. (38 ± 10), P <0.05] and executive function( inhibition)- Stroop T score [(35 ± 12) vs. (39 ± 10), P < 0.05] than AOS patients. No differences were fund in processing speed, verbal memory and learning, visual memory and learning (Ps >0.05) between the two groups. Conclusion: It suggests that the EOS patients have worse motor function, working memory and inhibition.
- Publication
Chinese Mental Health Journal / Zhongguo Xinli Weisheng Zazhi, 2019, Vol 33, Issue 3, p161
- ISSN
1000-6729
- Publication type
Article
- DOI
10.3969/j.issn.1000-6729.2019.03.001