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Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.
- Published in:
- Annals of the New York Academy of Sciences, 2018, v. 1418, n. 1, p. 5, doi. 10.1111/nyas.13531
- By:
- Publication type:
- Article
Transgenic overexpression of microRNA-30d in pancreatic beta-cells progressively regulates beta-cell function and identity.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16174-7
- By:
- Publication type:
- Article
Adaptation to chronic ER stress enforces pancreatic β-cell plasticity.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32425-7
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- Publication type:
- Article
Inflammatory Cytokines Rewire the Proinsulin Interaction Network in Human Islets.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 11, p. 3100, doi. 10.1210/clinem/dgac493
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- Publication type:
- Article
Defective Thyroglobulin: Cell Biology of Disease.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13605, doi. 10.3390/ijms232113605
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- Publication type:
- Article
Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring.
- Published in:
- Journal of Clinical Investigation, 2014, v. 124, n. 10, p. 4395, doi. 10.1172/JCI74237
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- Publication type:
- Article
Dominant protein interactions that influence the pathogenesis of conformational diseases.
- Published in:
- Journal of Clinical Investigation, 2013, v. 123, n. 7, p. 3124, doi. 10.1172/JCI67260
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- Publication type:
- Article
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone.
- Published in:
- 2008
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- Publication type:
- journal article
Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus.
- Published in:
- 2008
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- Publication type:
- journal article
Quantitative H<sub>2</sub>S-mediated protein sulfhydration reveals metabolic reprogramming during the Integrated Stress Response.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.10067
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- Publication type:
- Article
PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26225-8
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- Publication type:
- Article
SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.
- Published in:
- Diabetologia, 2023, v. 66, n. 11, p. 2042, doi. 10.1007/s00125-023-05979-4
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- Publication type:
- Article
Erratum to: Autophagy is a major regulator of beta cell insulin homeostasis.
- Published in:
- 2016
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- Publication type:
- Erratum
Autophagy is a major regulator of beta cell insulin homeostasis.
- Published in:
- Diabetologia, 2016, v. 59, n. 7, p. 1480, doi. 10.1007/s00125-016-3868-9
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- Publication type:
- Article
Intracellular Retention of Newly Synthesized Insulin in Yeast is Caused by Endoproteolytic...
- Published in:
- Journal of Cell Biology, 2001, v. 153, n. 6, p. 1187, doi. 10.1083/jcb.153.6.1187
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- Publication type:
- Article
Biosynthesis, structure, and folding of the insulin precursor protein.
- Published in:
- Diabetes, Obesity & Metabolism, 2018, v. 20, p. 28, doi. 10.1111/dom.13378
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- Publication type:
- Article
Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39978-1
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- Publication type:
- Article
Sox17 Regulates Insulin Secretion in the Normal and Pathologic Mouse β Cell.
- Published in:
- PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104675
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- Publication type:
- Article
Mutant INS-Gene Induced Diabetes of Youth: Proinsulin Cysteine Residues Impose Dominant-Negative Inhibition on Wild-Type Proinsulin Transport.
- Published in:
- PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013333
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- Publication type:
- Article
XB130 Plays an Essential Role in Folliculogenesis Through Mediating Interactions Between Microfilament and Microtubule Systems in Thyrocytes.
- Published in:
- Thyroid, 2022, v. 32, n. 2, p. 128, doi. 10.1089/thy.2021.0461
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- Publication type:
- Article
XB130 Deficiency Causes Congenital Hypothyroidism in Mice due to Disorganized Apical Membrane Structure and Function of Thyrocytes.
- Published in:
- Thyroid, 2021, v. 31, n. 11, p. 1650, doi. 10.1089/thy.2021.0195
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- Publication type:
- Article
86th Annual Meeting of the American Thyroid Association.
- Published in:
- 2016
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- Publication type:
- Editorial
Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro.
- Published in:
- EMBO Journal, 2015, v. 34, n. 13, p. 1759, doi. 10.15252/embj.201591058
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- Publication type:
- Article
G209R Mutant Mouse as a Model for Human PCSK1 Polyendocrinopathy.
- Published in:
- Endocrinology, 2022, v. 163, n. 5, p. 1, doi. 10.1210/endocr/bqac024
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- Publication type:
- Article
Autophagy of the ER: the secretome finds the lysosome.
- Published in:
- FEBS Journal, 2023, v. 290, n. 24, p. 5656, doi. 10.1111/febs.16986
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- Publication type:
- Article
Similarities and Differences among Neuroendocrine, Exocrine, and Endocytic Vesiclesa.
- Published in:
- Annals of the New York Academy of Sciences, 1987, v. 493, n. 1, p. 448, doi. 10.1111/j.1749-6632.1987.tb27230.x
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- Publication type:
- Article
Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence.
- Published in:
- Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.650158
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- Publication type:
- Article
Distinct states of proinsulin misfolding in MIDY.
- Published in:
- Cellular & Molecular Life Sciences, 2021, v. 78, n. 16, p. 6017, doi. 10.1007/s00018-021-03871-1
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- Publication type:
- Article
Deficient endoplasmic reticulum translocon-associated protein complex limits the biosynthesis of proinsulin and insulin.
- Published in:
- FASEB Journal, 2021, v. 35, n. 5, p. 1, doi. 10.1096/fj.202002774R
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- Publication type:
- Article
Preservation of circadian rhythms by the protein folding chaperone, BiP.
- Published in:
- FASEB Journal, 2019, v. 33, n. 6, p. 7479, doi. 10.1096/fj.201802366RR
- By:
- Publication type:
- Article
Normal and defective pathways in biogenesis and maintenance of the insulin storage pool.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.
- Published in:
- 2018
- By:
- Publication type:
- journal article
ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis.
- Published in:
- 2017
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- Publication type:
- journal article
Insulin demand regulates β cell number via the unfolded protein response.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Dominant-Negative Behavior of Mammalian Vps35 in Yeast Requires a Conserved PRLYL Motif Involved in Retromer Assembly.
- Published in:
- Traffic, 2007, v. 8, n. 12, p. 1829, doi. 10.1111/j.1600-0854.2007.00658.x
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- Publication type:
- Article
Structural Features of Vps35p Involved in Interaction with Other Subunits of the Retromer Complex.
- Published in:
- Traffic, 2007, v. 8, n. 12, p. 1841, doi. 10.1111/j.1600-0854.2007.00659.x
- By:
- Publication type:
- Article
Traffic Interchange Sorting Ourselves Out: Seeking Consensus on Trafficking in the Beta-Cell.
- Published in:
- 2004
- By:
- Publication type:
- Other
Secretory Pathway Quality Control Operating in Golgi, Plasmalemmal, and Endosomal Systems.
- Published in:
- Traffic, 2002, v. 3, n. 11, p. 771, doi. 10.1034/j.1600-0854.2002.31102.x
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- Publication type:
- Article
The structure of natively iodinated bovine thyroglobulin.
- Published in:
- Acta Crystallographica: Section D, Structural Biology, 2021, v. 77, n. 11, p. 1451, doi. 10.1107/S2059798321010056
- By:
- Publication type:
- Article
Protein disulfide isomerase-like proteins play opposing roles during retrotranslocation.
- Published in:
- Journal of Cell Biology, 2006, v. 173, n. 6, p. 853, doi. 10.1083/jcb.200602046
- By:
- Publication type:
- Article
Improved in vivo imaging method for individual islets across the mouse pancreas reveals a heterogeneous insulin secretion response to glucose.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79727-8
- By:
- Publication type:
- Article
Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 6, p. 975, doi. 10.3390/cells11060975
- By:
- Publication type:
- Article
Intracellular Protein Transport to the Thyrocyte Plasma Membrane: Potential Implications for Thyroid Physiology.
- Published in:
- Thyroid, 1997, v. 7, n. 1, p. 89, doi. 10.1089/thy.1997.7.89
- By:
- Publication type:
- Article
Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology.
- Published in:
- PLoS Genetics, 2009, v. 5, n. 10, p. 1, doi. 10.1371/journal.pgen.1000691
- By:
- Publication type:
- Article
Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264.
- Published in:
- 2019
- By:
- Publication type:
- Letter
Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Simultaneous Measurement of Changes in Mitochondrial and Endoplasmic Reticulum Free Calcium in Pancreatic Beta Cells.
- Published in:
- Biosensors (2079-6374), 2023, v. 13, n. 3, p. 382, doi. 10.3390/bios13030382
- By:
- Publication type:
- Article
Structural features of thyroglobulin linked to protein trafficking.
- Published in:
- Protein Science: A Publication of the Protein Society, 2023, v. 32, n. 11, p. 1, doi. 10.1002/pro.4784
- By:
- Publication type:
- Article
Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity.
- Published in:
- 2022
- By:
- Publication type:
- journal article