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- Title
The UPs and DOWNs of MITF in melanoma resistance.
- Authors
Kim, Hyungsoo; Ronai, Ze'ev A.
- Abstract
The article reports on the advantages and disadvantages of microphthalmia-associated transcription factor (MITF) in the resistance of melanoma. It mentions that its mutation has driven the creation of medical care for inhibiting the BRAF gene. It also notes that its growth was terminated through AXL and ERK inhibitors.
- Subjects
MICROPHTHALMIA-associated transcription factor; MELANOMA treatment; BRAF genes; GENETIC mutation; HELIX-loop-helix motifs
- Publication
Pigment Cell & Melanoma Research, 2015, Vol 28, Issue 2, p132
- ISSN
1755-1471
- Publication type
Article
- DOI
10.1111/pcmr.12338