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Not all roads lead to the immune system: the genetic basis of multiple sclerosis severity.
Published in:
2023
By:
- Jokubaitis, Vilija G;
- Campagna, Maria Pia;
- Ibrahim, Omar;
- Stankovich, Jim;
- Kleinova, Pavlina;
- Matesanz, Fuencisla;
- Hui, Daniel;
- Eichau, Sara;
- Slee, Mark;
- Lechner-Scott, Jeannette;
- Lea, Rodney;
- Kilpatrick, Trevor J;
- Kalincik, Tomas;
- Jager, Philip L De;
- Beecham, Ashley;
- McCauley, Jacob L;
- Taylor, Bruce V;
- Vucic, Steve;
- Laverick, Louise;
- Vodehnalova, Karolina
Publication type:
journal article
Galanin is an autocrine myelin and oligodendrocyte trophic signal induced by leukemia inhibitory factor.
Published in:
Glia, 2015, v. 63, n. 6, p. 1005, doi. 10.1002/glia.22798
By:
- Gresle, Melissa M.;
- Butzkueven, Helmut;
- Perreau, Victoria M.;
- Jonas, Anna;
- Xiao, Junhua;
- Thiem, Stefan;
- Holmes, Fiona E.;
- Doherty, William;
- Soo, Pik‐Ying;
- Binder, Michele D.;
- Akkermann, Rainer;
- Jokubaitis, Vilija G.;
- Cate, Holly S.;
- Marriott, Mark P.;
- Gundlach, Andrew L.;
- Wynick, David;
- Kilpatrick, Trevor J.
Publication type:
Article
Editorial: Aging in multiple sclerosis: from childhood to old age, in women and men.
Published in:
Frontiers in Neurology, 2024, p. 1, doi. 10.3389/fneur.2024.1368420
By:
- Lugares, Alessandra;
- Jokubaitis, Vilija G.;
- Krysko, Kristen M.
Publication type:
Article
A role for HLA in mediating long-term multiple sclerosis outcomes?
Published in:
Multiple Sclerosis Journal, 2023, v. 29, n. 3, p. 314, doi. 10.1177/13524585221139767
By:
- Jokubaitis, Vilija G
Publication type:
Article
Family planning is the second most relevant factor for treatment decisions after disease activity – Commentary.
Published in:
Multiple Sclerosis Journal, 2020, v. 26, n. 6, p. 644, doi. 10.1177/1352458520907902
By:
- Jokubaitis, Vilija G;
- Dobson, Ruth
Publication type:
Article
Functional neuroplasticity in response to cerebello-thalamic injury underpins the clinical presentation of tremor in multiple sclerosis.
Published in:
Multiple Sclerosis Journal, 2020, v. 26, n. 6, p. 696, doi. 10.1177/1352458519837706
By:
- Boonstra, Frederique MC;
- Noffs, Gustavo;
- Perera, Thushara;
- Jokubaitis, Vilija G;
- Vogel, Adam P;
- Moffat, Bradford A;
- Butzkueven, Helmut;
- Evans, Andrew;
- van der Walt, Anneke;
- Kolbe, Scott C
Publication type:
Article
Parity is associated with long-term differences in DNA methylation at genes related to neural plasticity in multiple sclerosis.
Published in:
Clinical Epigenetics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13148-023-01438-4
By:
- Campagna, Maria Pia;
- Xavier, Alexandre;
- Stankovich, Jim;
- Maltby, Vicki E.;
- Slee, Mark;
- Yeh, Wei Z.;
- Kilpatrick, Trevor;
- Scott, Rodney J.;
- Butzkueven, Helmut;
- Lechner-Scott, Jeannette;
- Lea, Rodney A.;
- Jokubaitis, Vilija G.
Publication type:
Article
Whole-blood methylation signatures are associated with and accurately classify multiple sclerosis disease severity.
Published in:
Clinical Epigenetics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13148-022-01397-2
By:
- Campagna, Maria Pia;
- Xavier, Alexandre;
- Lea, Rodney A.;
- Stankovich, Jim;
- Maltby, Vicki E.;
- Butzkueven, Helmut;
- Lechner-Scott, Jeannette;
- Scott, Rodney J.;
- Jokubaitis, Vilija G.
Publication type:
Article
Epigenome-wide association studies: current knowledge, strategies and recommendations.
Published in:
Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01200-8
By:
- Campagna, Maria Pia;
- Xavier, Alexandre;
- Lechner-Scott, Jeannette;
- Maltby, Vicky;
- Scott, Rodney J.;
- Butzkueven, Helmut;
- Jokubaitis, Vilija G.;
- Lea, Rodney A.
Publication type:
Article
The Australian Multiple Sclerosis (MS) Immunotherapy Study: A Prospective, Multicentre Study of Drug Utilisation Using the MSBase Platform.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059694
By:
- Jokubaitis, Vilija G.;
- Spelman, Tim;
- Lechner-Scott, Jeannette;
- Barnett, Michael;
- Shaw, Cameron;
- Vucic, Steve;
- Liew, Danny;
- Butzkueven, Helmut;
- Slee, Mark;
- on behalf of the Australian MSBase Study Group
Publication type:
Article
Country, Sex, EDSS Change and Therapy Choice Independently Predict Treatment Discontinuation in Multiple Sclerosis and Clinically Isolated Syndrome.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038661
By:
- Meyniel, Claire;
- Spelman, Timothy;
- Jokubaitis, Vilija G.;
- Trojano, Maria;
- Izquierdo, Guillermo;
- Grand'Maison, François;
- Oreja-Guevara, Celia;
- Boz, Cavit;
- Lugaresi, Alessandra;
- Girard, Marc;
- Grammond, Pierre;
- Iuliano, Gerardo;
- Fiol, Marcela;
- Cabrera-Gomez, Jose Antonio;
- Fernandez-Bolanos, Ricardo;
- Giuliani, Giorgio;
- Lechner-Scott, Jeannette;
- Cristiano, Edgardo;
- Herbert, Joseph;
- Petkovska-Boskova, Tatjana
Publication type:
Article
Ceruloplasmin gene-deficient mice with experimental autoimmune encephalomyelitis show attenuated early disease evolution.
Published in:
Journal of Neuroscience Research, 2014, v. 92, n. 6, p. 732, doi. 10.1002/jnr.23349
By:
- Gresle, Melissa M.;
- Schulz, Katrin;
- Jonas, Anna;
- Perreau, Victoria M.;
- Cipriani, Tania;
- Baxter, Alan G.;
- Miranda‐Hernandez, Socorro;
- Field, Judith;
- Jokubaitis, Vilija G.;
- Cherny, Robert;
- Volitakis, Irene;
- David, Samuel;
- Kilpatrick, Trevor J.;
- Butzkueven, Helmut
Publication type:
Article
Gas6 Deficiency Increases Oligodendrocyte Loss and Microglial Activation in Response to Cuprizone-Induced Demyelination.
Published in:
Journal of Neuroscience, 2008, v. 28, n. 20, p. 5195, doi. 10.1523/JNEUROSCI.1180-08.2008
By:
- Binder, Michele D.;
- Cate, Holly S.;
- Prieto, Anne L.;
- Kemper, Dennis;
- Butzkueven, Helmut;
- Gresle, Melissa M.;
- Cipriani, Tania;
- Jokubaitis, Vilija G.;
- Carmeliet, Peter;
- Kilpatrick, Trevor J.
Publication type:
Article
Association of Pregnancy With the Onset of Clinically Isolated Syndrome.
Published in:
JAMA Neurology, 2020, v. 77, n. 12, p. 1496, doi. 10.1001/jamaneurol.2020.3324
By:
- Nguyen, Ai-Lan;
- Vodehnalova, Karolina;
- Kalincik, Tomas;
- Signori, Alessio;
- Havrdova, Eva Kubala;
- Lechner-Scott, Jeannette;
- Skibina, Olga G.;
- Eastaugh, Alana;
- Taylor, Lisa;
- Baker, Josephine;
- McGuinn, Nicola;
- Rath, Louise;
- Maltby, Vicki;
- Sormani, Maria Pia;
- Butzkueven, Helmut;
- Van der Walt, Anneke;
- Horakova, Dana;
- Jokubaitis, Vilija G.
Publication type:
Article
Interferon beta treatment is a potent and targeted epigenetic modifier in multiple sclerosis.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1162796
By:
- Xavier, Alexandre;
- Campagna, Maria Pia;
- Maltby, Vicki E.;
- Kilpatrick, Trevor;
- Taylor, Bruce V.;
- Butzkueven, Helmut;
- Ponsonby, Anne-Louise;
- Scott, Rodney J.;
- Jokubaitis, Vilija G.;
- Lea, Rodney A.;
- Lechner-Scott, Jeannette
Publication type:
Article
Increased risk of cervical dysplasia in females with autoimmune conditions—Results from an Australia database linkage study.
Published in:
PLoS ONE, 2020, v. 15, n. 6, p. 1, doi. 10.1371/journal.pone.0234813
By:
- Foster, Emma;
- Malloy, Michael J.;
- Jokubaitis, Vilija G.;
- Wrede, C. David H.;
- Butzkueven, Helmut;
- Sasadeusz, Joe;
- Van Doornum, Sharon;
- Macrae, Finlay;
- Unglik, Gary;
- Brotherton, Julia M. L.;
- van der Walt, Anneke
Publication type:
Article
Risk of cervical pre-cancer and cancer in women with multiple sclerosis exposed to high efficacy disease modifying therapies.
Published in:
Frontiers in Neurology, 2023, v. 14, p. 01, doi. 10.3389/fneur.2023.1119660
By:
- Bridge, Francesca;
- Brotherton, Julia M. L.;
- Yi Foong;
- Butzkueven, Helmut;
- Jokubaitis, Vilija G.;
- Van der Walt, Anneke
Publication type:
Article
Predictors of long-term disability accrual in relapse-onset multiple sclerosis.
Published in:
2016
By:
- Jokubaitis, Vilija G.;
- Spelman, Tim;
- Kalincik, Tomas;
- Lorscheider, Johannes;
- Havrdova, Eva;
- Horakova, Dana;
- Duquette, Pierre;
- Girard, Marc;
- Prat, Alexandre;
- Izquierdo, Guillermo;
- Grammond, Pierre;
- Van Pesch, Vincent;
- Pucci, Eugenio;
- Grand'Maison, François;
- Hupperts, Raymond;
- Granella, Franco;
- Sola, Patrizia;
- Bergamaschi, Roberto;
- Iuliano, Gerardo;
- Spitaleri, Daniele
Publication type:
journal article
The MSBase pregnancy, neonatal outcomes, and women's health registry.
Published in:
Therapeutic Advances in Neurological Disorders, 2021, p. 1, doi. 10.1177/17562864211009104
By:
- Jokubaitis, Vilija G.;
- Skibina, Olga;
- Alroughani, Raed;
- Altintas, Ayse;
- Butzkueven, Helmut;
- Eichau, Sara;
- Fragoso, Yara;
- Hellwig, Kerstin;
- Hughes, Stella E.;
- Rath, Louise;
- van der Walt, Anneke;
- Gray, Orla
Publication type:
Article
High rates of JCV seroconversion in a large international cohort of natalizumab-treated patients.
Published in:
Therapeutic Advances in Neurological Disorders, 2021, p. 1, doi. 10.1177/1756286421998915
By:
- Dwyer, Christopher M.;
- Jokubaitis, Vilija G.;
- Stankovich, Jim;
- Baker, Josephine;
- Haartsen, Jodi;
- Butzkueven, Helmut;
- Cartwright, Adriana;
- Shuey, Neil;
- Fragoso, Yara Dadalti;
- Rath, Louise;
- Skibina, Olga;
- Fryer, Kylie;
- Butler, Ernest;
- Coleman, Jennifer;
- MacIntrye, Jennifer;
- Macdonell, Richard;
- Walt, Anneke van der
Publication type:
Article
High rates of JCV seroconversion in a large international cohort of natalizumab-treated patients.
Published in:
Therapeutic Advances in Neurological Disorders, 2021, p. 1, doi. 10.1177/1756286421998915
By:
- Dwyer, Christopher M.;
- Jokubaitis, Vilija G.;
- Stankovich, Jim;
- Baker, Josephine;
- Haartsen, Jodi;
- Butzkueven, Helmut;
- Cartwright, Adriana;
- Shuey, Neil;
- Fragoso, Yara Dadalti;
- Rath, Louise;
- Skibina, Olga;
- Fryer, Kylie;
- Butler, Ernest;
- Coleman, Jennifer;
- MacIntrye, Jennifer;
- Macdonell, Richard;
- Walt, Anneke van der
Publication type:
Article
The MSBase pregnancy, neonatal outcomes, and women's health registry.
Published in:
Therapeutic Advances in Neurological Disorders, 2021, p. 1, doi. 10.1177/17562864211009104
By:
- Jokubaitis, Vilija G.;
- Skibina, Olga;
- Alroughani, Raed;
- Altintas, Ayse;
- Butzkueven, Helmut;
- Eichau, Sara;
- Fragoso, Yara;
- Hellwig, Kerstin;
- Hughes, Stella E.;
- Rath, Louise;
- van der Walt, Anneke;
- Gray, Orla
Publication type:
Article
Re: Genetics of multiple sclerosis severity: The importance of statistical power in replication studies and Re: From discovery to replication: Power and definitions matter for multiple sclerosis severity.
Published in:
2024
By:
- Campagna, Maria Pia;
- Lechner-Scott, Jeannette;
- Taylor, Bruce V;
- Havrdova, Eva Kubala;
- Matesanz, Fuencisla;
- Butzkueven, Helmut;
- Jokubaitis, Vilija G
Publication type:
Letter
No evidence for association between rs10191329 severity locus and longitudinal disease severity in 1813 relapse-onset multiple sclerosis patients from the MSBase registry.
Published in:
Multiple Sclerosis Journal, 2024, v. 30, n. 9, p. 1216, doi. 10.1177/13524585241240406
By:
- Campagna, Maria Pia;
- Havrdova, Eva Kubala;
- Horakova, Dana;
- Izquierdo, Guillermo;
- Matesanz, Fuencisla;
- Eichau, Sara;
- Lechner-Scott, Jeannette;
- Taylor, Bruce V;
- García-Sanchéz, Maria-Isabel;
- Alcina, Antonio;
- van der Walt, Anneke;
- Butzkueven, Helmut;
- Jokubaitis, Vilija G
Publication type:
Article
DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12576, doi. 10.3390/ijms241612576
By:
- Xavier, Alexandre;
- Maltby, Vicki E.;
- Ewing, Ewoud;
- Campagna, Maria Pia;
- Burnard, Sean M.;
- Tegner, Jesper N.;
- Slee, Mark;
- Butzkueven, Helmut;
- Kockum, Ingrid;
- Kular, Lara;
- Jokubaitis, Vilija G.;
- Kilpatrick, Trevor;
- Alfredsson, Lars;
- Jagodic, Maja;
- Ponsonby, Anne-Louise;
- Taylor, Bruce V.;
- Scott, Rodney J.;
- Lea, Rodney A.;
- Lechner-Scott, Jeannette
Publication type:
Article
Predictors of disability worsening in clinically isolated syndrome.
Published in:
Annals of Clinical & Translational Neurology, 2015, v. 2, n. 5, p. 479, doi. 10.1002/acn3.187
By:
- Jokubaitis, Vilija G.;
- Spelman, Tim;
- Kalincik, Tomas;
- Izquierdo, Guillermo;
- Grand'Maison, François;
- Duquette, Pierre;
- Girard, Marc;
- Lugaresi, Alessandra;
- Grammond, Pierre;
- Hupperts, Raymond;
- Cabrera‐Gomez, José;
- Oreja‐Guevara, Celia;
- Boz, Cavit;
- Giuliani, Giorgio;
- Fernández‐Bolaños, Ricardo;
- Iuliano, Gerardo;
- Lechner‐Scott, Jeannette;
- Verheul, Freek;
- Pesch, Vincent;
- Petkovska‐Boskova, Tatjana
Publication type:
Article

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