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Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.
Published in:
EMBO Journal, 1998, v. 17, n. 10, p. 2846, doi. 10.1093/emboj/17.10.2846
By:
- Günes, Çagatay;
- Heuchel, Rainer;
- Georgiev, Oleg;
- Müller, Karl-Heinz;
- Lichtlen, Peter;
- Blüthmann, Horst;
- Marino, Silvia;
- Aguzzi, Adriano;
- Schaffner, Walter
Publication type:
Article
The Role of TKS5 in Chromosome Stability and Bladder Cancer Progression.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14283, doi. 10.3390/ijms232214283
By:
- Wang, Wenya;
- Zheng, Xi;
- Azoitei, Anca;
- John, Axel;
- Zengerling, Friedemann;
- Wezel, Felix;
- Bolenz, Christian;
- Günes, Cagatay
Publication type:
Article
Grainyhead-Like 3 Influences Migration and Invasion of Urothelial Carcinoma Cells.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2959, doi. 10.3390/ijms22062959
By:
- Wezel, Felix;
- Lustig, Johannes;
- Azoitei, Anca;
- Liu, Junnan;
- Meessen, Sabine;
- Najjar, Gregoire;
- Zehe, Viktor;
- Faustmann, Philipp;
- Zengerling, Friedemann;
- John, Axel;
- Martini, Thomas;
- Bolenz, Christian;
- Günes, Cagatay;
- Leem, Sun-Hee
Publication type:
Article
Downregulation of ORP3 Correlates with Reduced Survival of Colon Cancer Patients with Advanced Nodal Metastasis and of Female Patients with Grade 3 Colon Cancer.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5894, doi. 10.3390/ijms21165894
By:
- Xu, Pengfei;
- Richter, Julia;
- Blatz, Annette;
- Gärtner, Fabian;
- Alberts, Roland;
- Azoitei, Anca;
- Makori, Wycliffe Arika;
- Meessen, Sabine;
- Knippschild, Uwe;
- Günes, Cagatay
Publication type:
Article
A Novel Tissue and Stem Cell Specific TERF1 Splice Variant Is Downregulated in Tumour Cells.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 85, doi. 10.3390/ijms21010085
By:
- Morcos, Yousef Ashraf Tawfik;
- Najjar, Gregoire;
- Meessen, Sabine;
- Witt, Britta;
- Azoitei, Anca;
- Kumar, Mukesh;
- Wakileh, Gamal;
- Schwarz, Klaus;
- Schrezenmeier, Hubert;
- Zengerling, Friedemann;
- Bolenz, Christian;
- Günes, Cagatay
Publication type:
Article
A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma.
Published in:
Canadian Journal of Gastroenterology & Hepatology, 2021, p. 1, doi. 10.1155/2021/8854432
By:
- Diesinger, Torsten;
- Lautwein, Alfred;
- Bergler, Sebastian;
- Buckert, Dominik;
- Renz, Christian;
- Dvorsky, Radovan;
- Buko, Vyacheslav;
- Kirko, Siarhei;
- Schneider, Edith;
- Kuchenbauer, Florian;
- Kumar, Mukesh;
- Günes, Cagatay;
- Genze, Felicitas;
- Büchele, Berthold;
- Simmet, Thomas;
- Haslbeck, Martin;
- Masur, Kai;
- Barth, Thomas;
- Müller-Enoch, Dieter;
- Wirth, Thomas
Publication type:
Article
Impaired CK1 Delta Activity Attenuates SV40-Induced Cellular Transformation In Vitro and Mouse Mammary Carcinogenesis In Vivo.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029709
By:
- Hirner, Heidrun;
- Günes, Cagatay;
- Bischof, Joachim;
- Wolff, Sonja;
- Grothey, Arnhild;
- Kühl, Marion;
- Oswald, Franz;
- Wegwitz, Florian;
- Bösl, Michael R.;
- Trauzold, Anna;
- Henne-Bruns, Doris;
- Peifer, Christian;
- Leithäuser, Frank;
- Deppert, Wolfgang;
- Knippschild, Uwe
Publication type:
Article
A Comparative Assessment of Replication Stress Markers in the Context of Telomerase.
Published in:
Cancers, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/cancers14092205
By:
- Meessen, Sabine;
- Najjar, Gregoire;
- Azoitei, Anca;
- Iben, Sebastian;
- Bolenz, Christian;
- Günes, Cagatay
Publication type:
Article
Shorter Leukocyte Telomere Length Is Associated with Worse Survival of Patients with Bladder Cancer and Renal Cell Carcinoma.
Published in:
Cancers, 2021, v. 13, n. 15, p. 3774, doi. 10.3390/cancers13153774
By:
- Zheng, Xi;
- Wezel, Felix;
- Azoitei, Anca;
- Meessen, Sabine;
- Wang, Wenya;
- Najjar, Gregoire;
- Wang, Xue;
- Kraus, Johann M.;
- Kestler, Hans A.;
- John, Axel;
- Zengerling, Friedemann;
- Bolenz, Christian;
- Günes, Cagatay
Publication type:
Article
Telomeres and Telomerase in the Development of Liver Cancer.
Published in:
Cancers, 2020, v. 12, n. 8, p. 2048, doi. 10.3390/cancers12082048
By:
- in der Stroth, Lena;
- Tharehalli, Umesh;
- Günes, Cagatay;
- Lechel, André
Publication type:
Article
Knockdown of UTX/KDM6A Enriches Precursor Cell Populations in Urothelial Cell Cultures and Cell Lines.
Published in:
Cancers, 2020, v. 12, n. 4, p. 1023, doi. 10.3390/cancers12041023
By:
- Lang, Alexander;
- Whongsiri, Patcharawalai;
- Yilmaz, Merve;
- Lautwein, Tobias;
- Petzsch, Patrick;
- Greife, Annemarie;
- Günes, Cagatay;
- Köhrer, Karl;
- Niegisch, Günter;
- Hoffmann, Michèle;
- Schulz, Wolfgang A.
Publication type:
Article
Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion.
Published in:
EMBO Journal, 2017, v. 36, n. 19, p. 2922, doi. 10.15252/embj.201797470
By:
- Meena, Jitendra K;
- Cerutti, Aurora;
- Beichler, Christine;
- Morita, Yohei;
- Bruhn, Christopher;
- Kumar, Mukesh;
- Kraus, Johann M;
- Speicher, Michael R;
- Wang, Zhao‐Qi;
- Kestler, Hans A;
- Fagagna, Fabrizio d'Adda di;
- Günes, Cagatay;
- Rudolph, Karl Lenhard
Publication type:
Article
Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion.
Published in:
EMBO Journal, 2015, v. 34, n. 10, p. 1371, doi. 10.15252/embj.201490070
By:
- Meena, Jitendra K;
- Cerutti, Aurora;
- Beichler, Christine;
- Morita, Yohei;
- Bruhn, Christopher;
- Kumar, Mukesh;
- Kraus, Johann M;
- Speicher, Michael R;
- Wang, Zhao‐Qi;
- Kestler, Hans A;
- d'Adda di Fagagna, Fabrizio;
- Günes, Cagatay;
- Rudolph, Karl Lenhard
Publication type:
Article
Telomere dysfunction puts the brakes on oncogene-induced cancers.
Published in:
EMBO Journal, 2012, v. 31, n. 13, p. 2833, doi. 10.1038/emboj.2012.162
By:
- Günes, Cagatay;
- Rudolph, Karl Lenhard
Publication type:
Article
Co-operative binding of two Trp repressor dimers to α- or β-centred trp operators.
Published in:
Molecular Microbiology, 1996, v. 20, n. 2, p. 375
By:
- Günes, Çagatay;
- Staacke, Detlev;
- Von Wilcken-Bergmann, Brigitte;
- Müller-Hill, Benno
Publication type:
Article
Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis.
Published in:
PLoS ONE, 2020, v. 15, n. 7, p. 1, doi. 10.1371/journal.pone.0235990
By:
- Diesinger, Torsten;
- Buko, Vyacheslav;
- Lautwein, Alfred;
- Dvorsky, Radovan;
- Belonovskaya, Elena;
- Lukivskaya, Oksana;
- Naruta, Elena;
- Kirko, Siarhei;
- Andreev, Viktor;
- Buckert, Dominik;
- Bergler, Sebastian;
- Renz, Christian;
- Schneider, Edith;
- Kuchenbauer, Florian;
- Kumar, Mukesh;
- Günes, Cagatay;
- Büchele, Berthold;
- Simmet, Thomas;
- Müller-Enoch, Dieter;
- Wirth, Thomas
Publication type:
Article
Loss of ORP3 induces aneuploidy and promotes bladder cancer cell invasion through deregulated microtubule and actin dynamics.
Published in:
Cellular & Molecular Life Sciences, 2023, v. 80, n. 10, p. 1, doi. 10.1007/s00018-023-04959-6
By:
- Wang, Xue;
- Liu, Junnan;
- Azoitei, Anca;
- Eiseler, Tim;
- Meessen, Sabine;
- Jiang, Wencheng;
- Zheng, Xi;
- Makori, Arika W.;
- Eckstein, Markus;
- Hartmann, Arndt;
- Stilgenbauer, Stephan;
- Elati, Mohamed;
- Hohwieler, Meike;
- Kleger, Alexander;
- John, Axel;
- Zengerling, Friedemann;
- Wezel, Felix;
- Bolenz, Christian;
- Günes, Cagatay
Publication type:
Article
Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice.
Published in:
Nature Communications, 2014, v. 5, n. 9, p. 4924, doi. 10.1038/ncomms5924
By:
- Missios, Pavlos;
- Zhou, Yuan;
- Guachalla, Luis Miguel;
- von Figura, Guido;
- Wegner, Andre;
- Chakkarappan, Sundaram Reddy;
- Binz, Tina;
- Gompf, Anne;
- Hartleben, Götz;
- Burkhalter, Martin D.;
- Wulff, Veronika;
- Günes, Cagatay;
- Sattler, Rui Wang;
- Song, Zhangfa;
- Illig, Thomas;
- Klaus, Susanne;
- Böhm, Bernhard O.;
- Wenz, Tina;
- Hiller, Karsten;
- Rudolph, K. Lenhard
Publication type:
Article
Telomerase stimulates ribosomal DNA transcription under hyperproliferative conditions.
Published in:
Nature Communications, 2014, v. 5, n. 8, p. 4599, doi. 10.1038/ncomms5599
By:
- Gonzalez, Omar Garcia;
- Assfalg, Robin;
- Koch, Sylvia;
- Schelling, Adrian;
- Meena, Jitendra K.;
- Kraus, Johann;
- Lechel, Andre;
- Katz, Sarah-Fee;
- Benes, Vladimir;
- Scharffetter-Kochanek, Karin;
- Kestler, Hans A.;
- Günes, Cagatay;
- Iben, Sebastian
Publication type:
Article
Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion.
Published in:
Cellular & Molecular Biology Letters, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s11658-024-00609-2
By:
- Liu, Junnan;
- Wang, Xue;
- Jiang, Wencheng;
- Azoitei, Anca;
- Eiseler, Tim;
- Eckstein, Markus;
- Hartmann, Arndt;
- Stilgenbauer, Stephan;
- Elati, Mohamed;
- Hohwieler, Meike;
- Kleger, Alexander;
- John, Axel;
- Wezel, Felix;
- Zengerling, Friedemann;
- Bolenz, Christian;
- Günes, Cagatay
Publication type:
Article
Characterization of SKAP/kinastrin isoforms: the N-terminus defines tissue specificity and Pontin binding.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 13, p. 2838, doi. 10.1093/hmg/ddw140
By:
- Cindric Vranesic, Anita;
- Reiche, Juliane;
- Hoischen, Christian;
- Wohlmann, Andreas;
- Bratsch, Jens;
- Friedrich, Karlheinz;
- Günes, Berkay;
- Cappallo-Obermann, Heike;
- Kirchhoff, Christiane;
- Diekmann, Stephan;
- Günes, Cagatay;
- Huber, Otmar
Publication type:
Article
CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein-T mice during mammary carcinogenesis.
Published in:
International Journal of Cancer, 2013, v. 132, n. 9, p. 2032, doi. 10.1002/ijc.27880
By:
- Kumar, Mukesh;
- Witt, Britta;
- Knippschild, Uwe;
- Koch, Sylvia;
- Meena, Jitendra K.;
- Heinlein, Christina;
- Weise, Julia M.;
- Krepulat, Frauke;
- Kuchenbauer, Florian;
- Iben, Sebastian;
- Rudolph, Karl‐Lenhard;
- Deppert, Wolfgang;
- Günes, Cagatay
Publication type:
Article
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration.
Published in:
BMC Biology, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12915-023-01553-x
By:
- Melzer, Michael Karl;
- Schirge, Silvia;
- Gout, Johann;
- Arnold, Frank;
- Srinivasan, Dharini;
- Burtscher, Ingo;
- Allgöwer, Chantal;
- Mulaw, Medhanie;
- Zengerling, Friedemann;
- Günes, Cagatay;
- Lickert, Heiko;
- Christoffels, Vincent M.;
- Liebau, Stefan;
- Wagner, Martin;
- Seufferlein, Thomas;
- Bolenz, Christian;
- Moon, Anne M.;
- Perkhofer, Lukas;
- Kleger, Alexander
Publication type:
Article

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