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- Title
Microsatellite Instability and DNA Ploidy in Colorectal Cancer.
- Authors
Søreide, Kjetil; Slewa, Aida; Stokkeland, Pål J.; van Diermen, Bianca; Janssen, Emiel A. M.; Søreide, Jon Arne; Baak, Jan P. A.; Kørner, Hartwig
- Abstract
The article focuses on a study to investigate the effect of microsatellite instability (MSI) and deoxyribonucleic acid (DNA) ploidy on surveillance after resection for colorectal cancer post-surgery. The study concluded that the patients who had microsatellite instable tumors were at increased risk for locoregional recurrence, whereas lymph node status predicted distant metastasis. Comments on ways to improve clinical surveillance and choice of modality are also presented.
- Subjects
COLON cancer; PATIENTS; SURGERY; MICROSATELLITE repeats; DNA; TUMORS; LYMPH nodes; METASTASIS
- Publication
Cancer (0008543X), 2009, Vol 115, Issue 2, p271
- ISSN
0008-543X
- Publication type
Article
- DOI
10.1002/cncr.24024