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- Title
Structure and Functions of the Mediator Complex.
- Authors
Putlyaev, E. V.; Ibragimov, A. N.; Lebedeva, L. A.; Georgiev, P. G.; Shidlovskii, Y. V.
- Abstract
Mediator is a key factor in the regulation of expression of RNA polymerase II-transcribed genes. Recent studies have shown that Mediator acts as a coordinator of transcription activation and participates in maintaining chromatin architecture in the cell nucleus. In this review, we present current concepts on the structure and functions of Mediator.
- Subjects
RNA polymerase II; GENETIC regulation; GENETIC transcription; CHROMATIN; CELL nuclei
- Publication
Biochemistry (00062979), 2018, Vol 83, Issue 4, p423
- ISSN
0006-2979
- Publication type
Article
- DOI
10.1134/S0006297918040132