We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Genetic Research on Male Spermatogenic Failure.
- Authors
CAO Yun -xia; GAO Ming
- Abstract
Approximately 10%-15% of couples are infertile, while male infertility is almost half of all infertility. Spermatogenic failure is a major cause of male infertility, which shows azoospermia or oligozoospermia. Studies showed that Y chromosome plays an important role in spermatogenesis, and that Yq microdeletions are related to male infertility. X chromosome, as a single copy and unique expression in male, also plays an important role in spermatogenesis. Studies on teratozoospermia and asthenozoospermia showed that four genes located on autosomal chromosomes (SPA TA 16, PICK1, CA TSPER and A URKC) probably involved in spermatogenic failure. In future, more and more new genetic tests will be developed and used in the clinical practice of spermatogenic failure, with the worldwide efforts.
- Subjects
INFERTILITY; MALE infertility; SPERMATOGENESIS; Y chromosome; X chromosome; GENETIC testing
- Publication
Journal of International Reproductive Health/Family Planning, 2014, Vol 33, Issue 3, p182
- ISSN
1674-1889
- Publication type
Article