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- Title
Neutrophil function in children following allogeneic hematopoietic stem cell transplant.
- Authors
Kent, Michael W.; Kelher, Marguerite R.; Silliman, Christopher C.; Quinones, Ralph
- Abstract
HSCT is a lifesaving procedure for children with malignant and non-malignant conditions. The conditioning regimen renders the patient severely immunocompromised and recovery starts with neutrophil ( PMN) engraftment. We hypothesize that children demonstrate minimal PMN dysfunction at engraftment and beyond, which is influenced by the stem cell source and the conditioning regimen. Peripheral blood was serially collected from children at 1 to 12 months following allogeneic HSCT. PMN superoxide (
- Subjects
IMMUNOCOMPROMISED patients; NEUTROPHILS; LEUCOCYTE elastase; HEMATOPOIETIC stem cell transplantation; STEM cells
- Publication
Pediatric Transplantation, 2016, Vol 20, Issue 5, p658
- ISSN
1397-3142
- Publication type
Article
- DOI
10.1111/petr.12714