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- Title
Laboratory Investigation of Myeloproliferative Neoplasms (MPNs).
- Authors
Busque, Lambert; Porwit, Anna; Day, Radmila; Olney, Harold J.; Leber, Brian; Éthier, Vincent; Sirhan, Shireen; Foltz, Linda; Prchal, Jaroslav; Kamel-Reid, Suzanne; Karsan, Aly; Gupta, Vikas
- Abstract
Objectives: To standardize diagnostic investigations for myeloproliferative neoplasms (MPNs) to increase homogeneity in patient care and to streamline diagnostic approaches in the most efficient and cost-effective manner. Methods: The development of Canadian expert consensus recommendations for the diagnosis of MPNs began with a review of the following: clinical evidence, daily practice, existing treatment guidelines, and availability of diagnostic tools. Each group member was assigned a specific topic, which they discussed with the entire group during several consensus meetings. Results: This document provides the Canadian MPN group's recommendations, proposed diagnostic algorithms, and background evidence upon which decisions were made. Conclusions: Standardization of diagnostic investigations will increase homogeneity in patient care and provide a foundation for future clinical research in this rapidly evolving therapeutic area. Streamlining diagnostic approaches in the most efficient and cost-effective manner will also result in significant cost saving for the health care system.
- Subjects
TUMOR diagnosis; MYELOPROLIFERATIVE neoplasms; COST effectiveness; MEDICAL care costs; STANDARDIZATION; DIAGNOSIS
- Publication
American Journal of Clinical Pathology, 2016, Vol 146, Issue 4, p408
- ISSN
0002-9173
- Publication type
Article
- DOI
10.1093/AJCP/AQW131