We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Rapid improvement of muscle weakness post‐thymectomy indicates good long‐term neurological outcome in patients with ocular myasthenia gravis.
- Authors
Geng, Y.; Dong, J.; Zhou, Q.
- Abstract
Background and purpose: This study was conducted to evaluate whether post‐thymectomy rapid remission of ocular myasthenia gravis (oMG) is a prognostic indicator of good long‐term neurological outcome. Methods: Eighty‐four oMG patients who underwent thymectomy at our institute were enrolled. The incidence of 5‐year complete stable remission (CSR) was compared between patients with rapid remission of MG status (<1 month after surgery) and those with non‐rapid remission. Results: Kaplan–Meier survival analysis indicated that the incidence of CSR was higher in oMG patients with rapid remission than in those without rapid remission (P < 0.001). Multivariate analysis showed that rapid remission (odds ratio 16.34, 95% confidence interval 3.58–74.60, P < 0.001) is an independent prognostic factor for CSR. Conclusion: Postoperative rapid remission of MG status predicts a higher likelihood of complete remission in patients with oMG.
- Subjects
THYMECTOMY; MYASTHENIA gravis; MUSCLE weakness; MULTIVARIATE analysis; SURVIVAL analysis (Biometry); ODDS ratio
- Publication
European Journal of Neurology, 2019, Vol 26, Issue 11, p1421
- ISSN
1351-5101
- Publication type
Article
- DOI
10.1111/ene.14036