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The end of omics? High dimensional single cell analysis in precision medicine.
Published in:
European Journal of Immunology, 2019, v. 49, n. 2, p. 212, doi. 10.1002/eji.201847758
By:
- Galli, Edoardo;
- Friebel, Ekaterina;
- Ingelfinger, Florian;
- Unger, Susanne;
- Núñez, Nicolás Gonzalo;
- Becher, Burkhard
Publication type:
Article
Deciphering imprints of impaired memory B-cell maturation in germinal centers of three patients with common variable immunodeficiency.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.959002
By:
- van Schouwenburg, Pauline;
- Unger, Susanne;
- Payne, Kathryn J.;
- Kaiser, Fabian M. P.;
- Pico-Knijnenburg, Ingrid;
- Pfeiffer, Jens;
- Hausmann, Oliver;
- Friedmann, David;
- Erbel, Michelle;
- Seidl, Maximilian;
- van Zessen, David;
- Stubbs, Andrew P.;
- van der Burg, Mirjam;
- Warnatz, Klaus
Publication type:
Article
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.
Published in:
Nature Medicine, 2014, v. 20, n. 12, p. 1410, doi. 10.1038/nm.3746
By:
- Schubert, Desirée;
- Bode, Claudia;
- Kenefeck, Rupert;
- Hou, Tie Zheng;
- Wing, James B;
- Kennedy, Alan;
- Bulashevska, Alla;
- Petersen, Britt-Sabina;
- Schäffer, Alejandro A;
- Grüning, Björn A;
- Unger, Susanne;
- Frede, Natalie;
- Baumann, Ulrich;
- Witte, Torsten;
- Schmidt, Reinhold E;
- Dueckers, Gregor;
- Niehues, Tim;
- Seneviratne, Suranjith;
- Kanariou, Maria;
- Speckmann, Carsten
Publication type:
Article
Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation—Immune signature correlates with response.
Published in:
British Journal of Haematology, 2023, v. 203, n. 2, p. 264, doi. 10.1111/bjh.19007
By:
- Apostolova, Petya;
- Kreutmair, Stefanie;
- Toffalori, Cristina;
- Punta, Marco;
- Unger, Susanne;
- Burk, Ann‐Cathrin;
- Wehr, Claudia;
- Maas‐Bauer, Kristina;
- Melchinger, Wolfgang;
- Haring, Eileen;
- Hoefflin, Rouven;
- Shoumariyeh, Khalid;
- Hupfer, Valerie;
- Lauer, Eliza Maria;
- Duquesne, Sandra;
- Lowinus, Theresa;
- Gonzalo Núñez, Nicolás;
- Alberti, Chiara;
- da Costa Pereira, Sara;
- Merten, Carla Helena
Publication type:
Article
Common variable immunodeficiency (CVID): exploring the multiple dimensions of a heterogeneous disease.
Published in:
Annals of the New York Academy of Sciences, 2012, v. 1250, n. 1, p. 41, doi. 10.1111/j.1749-6632.2011.06377.x
By:
- Salzer, Ulrich;
- Unger, Susanne;
- Warnatz, Klaus
Publication type:
Article
Follicular Helper T Cells in DiGeorge Syndrome.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01730
By:
- Klocperk, Adam;
- Paračková, Zuzana;
- Bloomfield, Markéta;
- Rataj, Michal;
- Pokorný, Jan;
- Unger, Susanne;
- Warnatz, Klaus;
- Šedivá, Anna
Publication type:
Article
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44703-7
By:
- Maas-Bauer, Kristina;
- Stell, Anna-Verena;
- Yan, Kai-Li;
- de Vega, Enrique;
- Vinnakota, Janaki Manoja;
- Unger, Susanne;
- Núñez, Nicolas;
- Norona, Johana;
- Talvard-Balland, Nana;
- Koßmann, Stefanie;
- Schwan, Carsten;
- Miething, Cornelius;
- Martens, Uta S.;
- Shoumariyeh, Khalid;
- Nestor, Rosa P.;
- Duquesne, Sandra;
- Hanke, Kathrin;
- Rackiewicz, Michal;
- Hu, Zehan;
- El Khawanky, Nadia
Publication type:
Article
High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100328
By:
- Rakhmanov, Mirzokhid;
- Sic, Heiko;
- Kienzler, Anne-Kathrin;
- Fischer, Beate;
- Rizzi, Marta;
- Seidl, Maximilian;
- Melkaoui, Kerstina;
- Unger, Susanne;
- Moehle, Luisa;
- Schmit, Nadine E.;
- Deshmukh, Sachin D.;
- Ayata, Cemil Korcan;
- Schuh, Wolfgang;
- Zhang, Zhibing;
- Cosset, François-Loic;
- Verhoeyen, Els;
- Peter, Hans-Hartmut;
- Voll, Reinhard E.;
- Salzer, Ulrich;
- Eibel, Hermann
Publication type:
Article
TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00951
By:
- Staniek, Julian;
- Lorenzetti, Raquel;
- Heller, Bianca;
- Janowska, Iga;
- Schneider, Pascal;
- Unger, Susanne;
- Warnatz, Klaus;
- Seidl, Maximilian;
- Venhoff, Nils;
- Thiel, Jens;
- Smulski, Cristian Roberto;
- Rizzi, Marta
Publication type:
Article
Identification of single-cell blasts in pediatric acute myeloid leukemia using an autoencoder.
Published in:
Life Science Alliance, 2024, v. 7, n. 11, p. 1, doi. 10.26508/lsa.202402674
By:
- Driessen, Alice;
- Unger, Susanne;
- An-phi Nguyen;
- Ries, Rhonda E.;
- Meshinchi, Soheil;
- Kreutmair, Stefanie;
- Alberti, Chiara;
- Sumazin, Pavel;
- Aplenc, Richard;
- Redell, Michele S.;
- Becher, Burkhard;
- Rodríguez Martínez, María
Publication type:
Article
The expansion of human T-bethighCD21low B cells is T cell dependent.
Published in:
Science Immunology, 2021, v. 6, n. 64, p. 1, doi. 10.1126/sciimmunol.abh0891
By:
- Keller, Baerbel;
- Strohmeier, Valentina;
- Harder, Ina;
- Unger, Susanne;
- Payne, Kathryn J.;
- Andrieux, Geoffroy;
- Boerries, Melanie;
- Felixberger, Peter Tobias;
- Landry, Jonathan J. M.;
- Nieters, Alexandra;
- Rensing-Ehl, Anne;
- Salzer, Ulrich;
- Frede, Natalie;
- Usadel, Susanne;
- Elling, Roland;
- Speckmann, Carsten;
- Hainmann, Ina;
- Ralph, Elizabeth;
- Gilmour, Kimberly;
- Wentink, Marjolein W. J.
Publication type:
Article
Bronchoalveolar Lavage Fluid Reflects a TH1-CD21low B-Cell Interaction in CVID-Related Interstitial Lung Disease.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.616832
By:
- Friedmann, David;
- Unger, Susanne;
- Keller, Baerbel;
- Rakhmanov, Mirzokhid;
- Goldacker, Sigune;
- Zissel, Gernot;
- Frye, Björn C.;
- Schupp, Jonas C.;
- Prasse, Antje;
- Warnatz, Klaus
Publication type:
Article
Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency–Associated Villous Atrophy and Norovirus Infection.
Published in:
Journal of Clinical Immunology, 2023, v. 43, n. 2, p. 371, doi. 10.1007/s10875-022-01379-2
By:
- Strohmeier, Valentina;
- Andrieux, Geoffroy;
- Unger, Susanne;
- Pascual-Reguant, Anna;
- Klocperk, Adam;
- Seidl, Maximilian;
- Marques, Otavio Cabral;
- Eckert, Marleen;
- Gräwe, Katja;
- Shabani, Michelle;
- von Spee-Mayer, Caroline;
- Friedmann, David;
- Harder, Ina;
- Gutenberger, Sylvia;
- Keller, Baerbel;
- Proietti, Michele;
- Bulashevska, Alla;
- Grimbacher, Bodo;
- Provaznik, Jan;
- Benes, Vladimir
Publication type:
Article
Distinct CD8 T Cell Populations with Differential Exhaustion Profiles Associate with Secondary Complications in Common Variable Immunodeficiency.
Published in:
Journal of Clinical Immunology, 2022, v. 42, n. 6, p. 1254, doi. 10.1007/s10875-022-01291-9
By:
- Klocperk, Adam;
- Friedmann, David;
- Schlaak, Alexandra Emilia;
- Unger, Susanne;
- Parackova, Zuzana;
- Goldacker, Sigune;
- Sediva, Anna;
- Bengsch, Bertram;
- Warnatz, Klaus
Publication type:
Article
Altered Spectrum of Lymphoid Neoplasms in a Single-Center Cohort of Common Variable Immunodeficiency with Immune Dysregulation.
Published in:
Journal of Clinical Immunology, 2021, v. 41, n. 6, p. 1250, doi. 10.1007/s10875-021-01016-4
By:
- Wehr, Claudia;
- Houet, Leonora;
- Unger, Susanne;
- Kindle, Gerhard;
- Goldacker, Sigune;
- Grimbacher, Bodo;
- Caballero Garcia de Oteyza, Andrés;
- Marks, Reinhard;
- Pfeifer, Dietmar;
- Nieters, Alexandra;
- Proietti, Michele;
- Warnatz, Klaus;
- Schmitt-Graeff, Annette
Publication type:
Article
T+ NK+ IL-2 Receptor γ Chain Mutation: a Challenging Diagnosis of Atypical Severe Combined Immunodeficiency.
Published in:
Journal of Clinical Immunology, 2018, v. 38, n. 4, p. 527, doi. 10.1007/s10875-018-0514-y
By:
- Stepensky, Polina;
- Keller, Baerbel;
- Shamriz, Oded;
- von Spee-Mayer, Caroline;
- Friedmann, David;
- Shadur, Bella;
- Unger, Susanne;
- Fuchs, Sebastian;
- NaserEddin, Adeeb;
- Rumman, Nisreen;
- Amro, Sara;
- Molho Pessach, Vered;
- Abuzaitoun, Omar;
- Somech, Raz;
- Elpeleg, Orly;
- Ehl, Stephan;
- Warnatz, Klaus
Publication type:
Article
Preferential Reduction of Circulating Innate Lymphoid Cells Type 2 in Patients with Common Variable Immunodeficiency with Secondary Complications Is Part of a Broader Immune Dysregulation.
Published in:
Journal of Clinical Immunology, 2017, v. 37, n. 8, p. 759, doi. 10.1007/s10875-017-0444-0
By:
- Friedmann, David;
- Keller, Baerbel;
- Harder, Ina;
- Schupp, Jonas;
- Tanriver, Yakup;
- Unger, Susanne;
- Warnatz, Klaus
Publication type:
Article
Secondary Antibody Deficiency in Glucocorticoid Therapy Clearly Differs from Primary Antibody Deficiency.
Published in:
Journal of Clinical Immunology, 2016, v. 36, n. 4, p. 406, doi. 10.1007/s10875-016-0264-7
By:
- Wirsum, Clemens;
- Glaser, Cornelia;
- Gutenberger, Sylvia;
- Keller, Baerbel;
- Unger, Susanne;
- Voll, Reinhard;
- Vach, Werner;
- Ness, Thomas;
- Warnatz, Klaus
Publication type:
Article
Enteroviral Infection in a Patient with BLNK Adaptor Protein Deficiency.
Published in:
Journal of Clinical Immunology, 2015, v. 35, n. 4, p. 356, doi. 10.1007/s10875-015-0164-2
By:
- NaserEddin, Adeeb;
- Shamriz, Oded;
- Keller, Baerbel;
- Alzyoud, Raed;
- Unger, Susanne;
- Fisch, Paul;
- Prus, Evgenia;
- Berkun, Yakov;
- Averbuch, Diana;
- Shaag, Avraham;
- Wahadneh, Adel;
- Conley, Mary;
- Warnatz, Klaus;
- Elpeleg, Orly;
- Stepensky, Polina
Publication type:
Article
Ill-Defined Germinal Centers and Severely Reduced Plasma Cells are Histological Hallmarks of Lymphadenopathy in Patients with Common Variable Immunodeficiency.
Published in:
Journal of Clinical Immunology, 2014, v. 34, n. 6, p. 615, doi. 10.1007/s10875-014-0052-1
By:
- Unger, Susanne;
- Seidl, Maximilian;
- Schmitt-Graeff, Annette;
- Böhm, Joachim;
- Schrenk, Klaudia;
- Wehr, Claudia;
- Goldacker, Sigune;
- Dräger, Ruth;
- Gärtner, Barbara;
- Fisch, Paul;
- Werner, Martin;
- Warnatz, Klaus
Publication type:
Article
Cytokines in Common Variable Immunodeficiency as Signs of Immune Dysregulation and Potential Therapeutic Targets - A Review of the Current Knowledge.
Published in:
Journal of Clinical Immunology, 2014, v. 34, n. 5, p. 524, doi. 10.1007/s10875-014-0053-0
By:
- Varzaneh, Farnaz;
- Keller, Bärbel;
- Unger, Susanne;
- Aghamohammadi, Asghar;
- Warnatz, Klaus;
- Rezaei, Nima
Publication type:
Article
Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15497-1
By:
- Hamarsheh, Shaima'a;
- Osswald, Lena;
- Saller, Benedikt S.;
- Unger, Susanne;
- De Feo, Donatella;
- Vinnakota, Janaki Manoja;
- Konantz, Martina;
- Uhl, Franziska M.;
- Becker, Heiko;
- Lübbert, Michael;
- Shoumariyeh, Khalid;
- Schürch, Christoph;
- Andrieux, Geoffroy;
- Venhoff, Nils;
- Schmitt-Graeff, Annette;
- Duquesne, Sandra;
- Pfeifer, Dietmar;
- Cooper, Matthew A.;
- Lengerke, Claudia;
- Boerries, Melanie
Publication type:
Article

Found: 22

The end of omics? High dimensional single cell analysis in precision medicine.

Deciphering imprints of impaired memory B-cell maturation in germinal centers of three patients with common variable immunodeficiency.

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.

Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation—Immune signature correlates with response.

Common variable immunodeficiency (CVID): exploring the multiple dimensions of a heterogeneous disease.

Follicular Helper T Cells in DiGeorge Syndrome.

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease.

High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation.

TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes.

Identification of single-cell blasts in pediatric acute myeloid leukemia using an autoencoder.

The expansion of human T-bet<sup>high</sup>CD21<sup>low</sup> B cells is T cell dependent.

Bronchoalveolar Lavage Fluid Reflects a T<sub>H</sub>1-CD21<sup>low</sup> B-Cell Interaction in CVID-Related Interstitial Lung Disease.

Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency–Associated Villous Atrophy and Norovirus Infection.

Distinct CD8 T Cell Populations with Differential Exhaustion Profiles Associate with Secondary Complications in Common Variable Immunodeficiency.

Altered Spectrum of Lymphoid Neoplasms in a Single-Center Cohort of Common Variable Immunodeficiency with Immune Dysregulation.

T<sup>+</sup> NK<sup>+</sup> IL-2 Receptor γ Chain Mutation: a Challenging Diagnosis of Atypical Severe Combined Immunodeficiency.

Preferential Reduction of Circulating Innate Lymphoid Cells Type 2 in Patients with Common Variable Immunodeficiency with Secondary Complications Is Part of a Broader Immune Dysregulation.

Secondary Antibody Deficiency in Glucocorticoid Therapy Clearly Differs from Primary Antibody Deficiency.

Enteroviral Infection in a Patient with BLNK Adaptor Protein Deficiency.

Ill-Defined Germinal Centers and Severely Reduced Plasma Cells are Histological Hallmarks of Lymphadenopathy in Patients with Common Variable Immunodeficiency.

Cytokines in Common Variable Immunodeficiency as Signs of Immune Dysregulation and Potential Therapeutic Targets - A Review of the Current Knowledge.

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation.