We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Simultaneous intradermal testing with hymenoptera venoms is safe and more efficient than sequential testing.
- Authors
Strohmeier, B.; Aberer, W.; Bokanovic, D.; Komericki, P.; Sturm, G. J.
- Abstract
Background According to current guidelines, skin testing for hymenoptera venom allergy should be performed in a stepwise manner, maintaining 15- to 20-min intervals between the injections of venom. Given the long-winded procedure of sequential skin testing, we retrospectively explored the safety of simultaneous intradermal testing. Methods Four hundred and seventy-eight consecutive patients with a convincing history of an anaphylactic reaction after a hymenoptera sting were tested. All venom concentrations (0.02 ml of 0.001, 0.01, 0.1, and 1.0 μg/ml of honey bee and wasp venom) were administered simultaneously to the skin. Results Four hundred and seventy-two (98.7%) patients tolerated the simultaneous intradermal test without any side-effects. Only three subjects (0.6%) had a presumed allergic reaction during the test; another three reactions were considered vasovagal. Conclusion Our skin test protocol with four simultaneously injected concentrations of two hymenoptera venoms is safe and permits the investigator to draw rapid conclusions about the individual's sensitization pattern.
- Subjects
HYMENOPTERA; VENOM; INTRADERMAL injections; POISONOUS animals; IMMUNOLOGIC diseases
- Publication
Allergy, 2013, Vol 68, Issue 4, p542
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.12123