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- Title
Intravitreal ranibizumab for choroidal neovascularization in a patient with angioid streaks and multiple evanescent white dots.
- Authors
Pece, Alfredo; Allegrini, Davide; Kontadakis, Stelios; Querques, Giuseppe; Rossetti, Luca
- Abstract
<bold>Background: </bold>To report a patient with angioid streaks (ASs) and coincident multiple evanescent white dot syndrome (MEWDS) who developed choroidal neovascularization (CNV).<bold>Case Presentation: </bold>A 20-year-old woman presented with reduced vision (20/100) in her left eye (LE). Based on a complete ophthalmologic examination the patient was diagnosed with ASs and coincident MEWDS. Two weeks later best-corrected visual acuity (BCVA) improved up to 20/25 and the MEWDS findings almost disappeared. Two months later BCVA dropped again (20/100) due to the development of CNV which was treated by a single intravitreal injection of ranibizumab (0.5 mg/0.05 mL). One month after this BCVA improved up to 20/40, and there was regression of the CNV. There was no need for retreatment at the last follow-up visit, 1 year after the ranibizumab injection, when the patient showed further recovery of BCVA up to 20/25.<bold>Conclusions: </bold>In this case of ASs, MEWDS completely resolved after 2 weeks, but 2 months later CNV developed. A single intravitreal injection of ranibizumab had a long-lasting effect. Larger series are necessary to clarify the pathogenesis of CNV in such cases and the role of intravitreal ranibizumab.
- Subjects
RANIBIZUMAB; ANTINEOPLASTIC agents; NEOVASCULARIZATION; RETINAL diseases; VISUAL acuity; PATIENTS
- Publication
BMC Ophthalmology, 2016, Vol 16, p1
- ISSN
1471-2415
- Publication type
journal article
- DOI
10.1186/s12886-016-0307-0