We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
L-Arginine Improves Post-Ischemic Vasodilation in Coronary Heart Disease Patients Taking Vasodilating Drugs.
- Authors
Lannuzzi, Arcangelo; Jannuzzo, Gabriella; Sapio, Cecilia; Pauciullo, Paolo; Iorio, Domenico; Nicola Spampinato; Mancini, Mario; Rubba, Paolo
- Abstract
The article reports that L-arginine improves post-ischemic vasodilation in coronary heart disease patients taking vasodilating drugs. Twenty patients with onset of symptoms of coronary artery disease before age 50, operated for aortocoronary bypass and taking vasodilating drugs, were compared with 20 control subjects of comparable age and gender. It is found that hemodynamic responses in the skeletal muscle are impaired during a reactive hyperemia test in relatively young coronary heart disease patients taking vasodilating drugs. Intravenous L-arginine infusion corrects the impaired vasodilatory response of the lower limbs to an acute increase in flow following a cuff thigh occlusion.
- Subjects
CORONARY disease; HEART diseases; ARGININE; AMINO acids; CORONARY artery bypass; PATIENTS
- Publication
Journal of Cardiovascular Pharmacology & Therapeutics, 2001, Vol 6, Issue 2, p121
- ISSN
1074-2484
- Publication type
Article
- DOI
10.1177/107424840100600203