We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A study of prognostic significance of serum troponin I in patients with acute ischaemic stroke.
- Authors
Pynam, Pranuthi; Vengamma, B.; Prasad, S. V. Naveen; Challa, Sai Neelima; Rakesh, R.
- Abstract
Background: Serum troponins have also been reported to be elevated in patients with acute cerebrovascular disease and poor clinical outcome. Methods: We prospectively evaluated 360 patients with acute ischaemic stroke (AIS) to study the relationship between serum troponin I (TnI) levels and severity of AIS and to compare serum TnI levels in patients with favourable and unfavourable functional outcomes. Results: Their mean age was 58.8 ± 13.3 years; there were 230 (63.9%) males. Majority (n = 288; 80%) had presented with anterior circulation stroke and 58 (16.1%) had posterior circulation stroke. Majority (52.5%) had large artery atherosclerosis. The median (interquartile range) National Institutes of Health Stroke Scale (NIHSS) score was 18 (16-20). Serum TnI was positive in 87 (24.2%) and negative in 273 (75.8%). The NIHSS score at admission was higher in the positive serum TnI group. Moderate-to-severe stroke, severe stroke and cardioembolic stroke were more frequently seen in the serum TnI-positive group. Outcome was favourable in 157 (47.7%) and unfavourable outcome was seen in 172 (52.3%) patients. Conclusions: Elevated serum TnI levels were associated with increased severity of AIS and poor functional outcome.
- Subjects
NATIONAL Institutes of Health (U.S.); TROPONIN I; STROKE; CEREBROVASCULAR disease; SERUM; ACUTE diseases; COLLATERAL circulation
- Publication
Journal of Clinical & Scientific Research, 2020, Vol 9, Issue 1, p11
- ISSN
2277-5706
- Publication type
Article
- DOI
10.4103/JCSR.JCSR_87_19