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- Title
Bioactive Secondary Metabolites from Tecomella undulata.
- Authors
Ahmad, Shabir; Musaddiq, Sara; Saleem, Muhammad; Riaz, Naheed; Fatima, Sundas; Yaqoob, Asma; Jabbar, Abdul; Nasim, Faiz-ul-Hassan
- Abstract
Chromatographic purification of the methanolic extract of Tecomella undulata yielded a new flavonoid glycoside; kaempferol-3-O-β-D-[3''',4'''di-p-E-coumaroyl-α-L-rhamnosyl(1→6)] galactoside (1), two new megastigmanes; (6R 7Z)-9,10-dihydroxy-4,7-megastigmadien-3-one (2) and (6E)-9,10-dihydroxy-4,6-megastigmadien-3-one (3) along with three known compounds; (6R 9S)-9,10-dihydroxy-4-megastigmaen-3-one (4) quercetin-3-galactoside (5) and 3'-dimethoxy-5,6,4'-trihydroxyflavon (6). All the isolates 1-6 were characterized by the combination of 1D (1H, 13C), 2D (COSY, HSQC and HMBC) NMR data and high resolution mass spectrometric analysis. In antibacterial assay, compound 1 showed moderate inhibitory activity against Escherichia coli and Salmonalla typhi.
- Subjects
BIOACTIVE compounds; PLANT products; METABOLITES; FLAVONOID glycosides; GALACTOSIDES; MASS spectrometry; ANTIBACTERIAL agents; CHROMATOGRAPHIC analysis
- Publication
Journal of the Chemical Society of Pakistan, 2014, Vol 36, Issue 6, p1122
- ISSN
0253-5106
- Publication type
Article