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- Title
Synthesis and Characterization of an Antioxidative Galactomannan–Iron(III) Complex from Sesbania Seed.
- Authors
Huang, Caoxing; Tao, Yuheng; Li, Min; Zhang, Weiyu; Fan, Yimin; Yong, Qiang
- Abstract
Galactomannan, a water-soluble polymer in the cell wall of leguminous plants, has been proven to possess anticancer and antioxidative activity. In this work, galactomannan with different molecular weights (GM-40 and GM-65) was obtained from Sesbania seeds and synthesized into galactomannan–iron(III) complexes, which are termed as GM-40-Fe and GM-65-Fe, respectively. These galactomannan–iron(III) complexes are intended to function as organic iron supplements to treat iron deficiency with the added benefit of antioxidative activity. The prepared galactomannan–iron(III) complexes were characterized for chemical composition, morphology, antioxidant capacity, and bioavailability in vitro. The results showed that galactomannan–iron(III) complexes could be produced with iron contents as high as 65.4 mg/g. Antioxidant assays indicated that both GM-40-Fe and GM-65-Fe exhibited antioxidant activities for scavenging radicals in vitro. The iron release/bioavailability assays showed that the iron was easily released into artificial gastric and intestinal juices, resulting in iron release rates of 88–94% over 300 min. These results suggest that galactomannan–iron(III) complexes synthesized from Sesbania seed polysaccharides are capable of being administered as organic iron supplements to patients with iron deficiency.
- Subjects
ANTIOXIDANTS; SESBANIA; GALACTOMANNANS; MOLECULAR weights; IRON deficiency
- Publication
Polymers (20734360), 2019, Vol 11, Issue 1, p28
- ISSN
2073-4360
- Publication type
Article
- DOI
10.3390/polym11010028