We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Cell cycle block by p53 activation reduces SARS-CoV-2 release in A549- hAce2 cells.
- Authors
Lodi, Giada; Gentili, Valentina; Casciano, Fabio; Romani, Arianna; Zauli, Giorgio; Secchiero, Paola; Beltrami, Silvia; Fernandez, Mercedes; Rizzo, Roberta; Voltan, Rebecca
- Abstract
The article focuses on using MDM2 inhibitors like Nutlin-3 and RG-7112 to raise p53 levels and activate p53-dependent pathways as a potential approach to reduce SARS-CoV-2 replication and inflammation, suggesting that p53 could be a valuable target for new therapies against the virus.
- Publication
Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2023, p240
- ISSN
1122-6714
- Publication type
Article