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- Title
Canadian guideline for Parkinson disease.
- Authors
Grimes, David; Fitzpatrick, Megan; Gordon, Joyce; Miyasaki, Janis; Fon, Edward A.; Schlossmacher, Michael; Suchowersky, Oksana; Rajput, Alexander; Lafontaine, Anne Louise; Mestre, Tiago; Appel-Cresswell, Silke; Kalia, Suneil K.; Schoffer, Kerrie; Zurowski, Mateusz; Postuma, Ronald B.; Udow, Sean; Fox, Susan; Barbeau, Pauline; Hutton, Brian
- Abstract
High-quality systematic reviews of case-control or cohort studies</td></tr><tr><td valign="top">2++</td><td valign="top">High-quality case-control or cohort studies with a very low risk of confounding or bias and a high probability that the relationship is causal</td></tr><tr><td valign="top">2+</td><td valign="top">Well-conducted case-control or cohort studies with a low risk of confounding or bias and a moderate probability that the relationship is causal</td></tr><tr><td valign="top">2-</td><td valign="top">Case-control or cohort studies with a high risk of confounding or bias and a substantial risk that the relationship is not causal</td></tr><tr><td valign="top">3</td><td valign="top">Nonanalytic studies (e.g., case reports, case series). When symptoms appear suddenly, exclude urinary tract infection.</td><td valign="top">EFNS<xref ref-type="bibr" rid="bibr15">15</xref></td><td valign="top">GPP</td></tr><tr><td valign="top" /><td valign="top">• Nocturia: reduce intake of fluid after 6 pm. These require reports of subjective cognitive decline and difficulties on psychometric testing.</td><td valign="top">CAN</td><td valign="top">GPP</td></tr><tr><td colspan="4" valign="top" /></tr><tr><td valign="top">C74</td><td valign="top">For PD dementia, cholinesterase inhibitors could be added: rivastigmine (grade: A), donepezil (grade: A), or galantamine (grade: C).
- Subjects
DYSKINESIAS; PARKINSON'S disease; MEDICAL personnel; PROGRESSIVE supranuclear palsy; SINGLE-photon emission computed tomography; RAPID eye movement sleep
- Publication
Canadian Medical Association Journal (CMAJ), 2019, Vol 191, Issue 36, pE989
- Publication type
journal article
- DOI
10.1503/cmaj.181504