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- Title
Heart rate response to vasodilator stress: A potential new application for a proven prognostic parameter.
- Authors
Schumann, Christopher L.; Bourque, Jamieson M.
- Abstract
A prospective randomized trial was initiated comparing SP 123 sp I-MIBG H/M ratio-guided ICD implantation to a guidelines-directed approach for patients with NYHA class II-III heart failure and LVEF 25-35%. They investigate the relationship between HRR during pharmacological stress testing and myocardial innervation using SP 123 sp I-MIBG cardiac scintigraphy in 71 patients with known or suspected coronary artery disease. See related article, https://doi.org/10.1007/s12350-020-02091-7 While the focus of stress testing has traditionally been on the evaluation of electrocardiographic or imaging evidence of ischemia, the hemodynamic response to stress offers a wealth of both diagnostic and prognostic information to the clinician beyond this one application. It is important to note that while large prospective randomized trials have not been completed to verify the utility of cardiac SNS imaging in the management of heart failure patients, there are several promising applications of this imaging modality.
- Subjects
HEART beat; HEART failure; DYSAUTONOMIA; HEALTH insurance reimbursement; HEART failure patients; PROGNOSIS; MYOCARDIAL perfusion imaging; IMPLANTABLE cardioverter-defibrillators
- Publication
Journal of Nuclear Cardiology, 2021, Vol 28, Issue 6, p2684
- ISSN
1071-3581
- Publication type
Editorial
- DOI
10.1007/s12350-020-02168-3