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- Title
Differential effects of variation in athletes training on myocardial morphophysiological adaptation in men: focus on ¹²³I-MIBG assessed myocardial sympathetic activity.
- Authors
Miranda, Douglas Pinheiro; Dos Santos, Marcelo José; Salemi, Vera Maria Cury; de Oliveira, Edmundo Pereira Caparelli; Verberne, Hein J; da Rocha, Euclides Timóteo
- Abstract
<bold>Purpose: </bold>High intensity systematic physical training leads to myocardial morphophysiological adaptations. The goal of this study was to investigate if differences in training were correlated with differences in cardiac sympathetic activity.<bold>Methods: </bold>58 males (19-47 years), were divided into three groups: strength group (SG), (20 bodybuilders), endurance group (EG), (20 endurance athletes), and a control group (CG) comprising 18 healthy non-athletes. Cardiac sympathetic innervation was assessed by planar myocardial (123)I-metaiodobenzylguanidine scintigraphy using the early and late heart to mediastinal (H/M) ratio, and washout rate (WR).<bold>Results: </bold>Left ventricular mass index was significantly higher both in SG (P < .001) and EG (P = .001) compared to CG without a statistical significant difference between SG and EG (P = .417). The relative wall thickness was significantly higher in SG compared to CG (P < .001). Both left ventricular ejection fraction and the peak filling rate showed no significant difference between the groups. Resting heart rate was significantly lower in EG compared to CG (P = .006) and SG (P = .002). The late H/M ratio in CG was significantly higher compared to the late H/M for SG (P = .003) and EG (P = .004). However, WR showed no difference between the groups. There was no significant correlation between the parameters of myocardial sympathetic innervation and parameters of left ventricular function.<bold>Conclusions: </bold>Strength training resulted in a significant increase in cardiac dimensions. Both strength and endurance training seem to cause a reduction in myocardial sympathetic drive. However, myocardial morphological and functional adaptations to training were not correlated with myocardial sympathetic activity.
- Publication
Journal of Nuclear Cardiology, 2014, Vol 21, Issue 3, p570
- ISSN
1071-3581
- Publication type
journal article
- DOI
10.1007/s12350-014-9876-6