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- Title
Right ventricular peak systolic longitudinal strain is a sensitive marker for right ventricular deterioration in adult patients with tetralogy of Fallot.
- Authors
Scherptong, Roderick W. C.; Mollema, Sjoerd A.; Blom, Nico A.; Kroft, Lucia J. M.; de Roos, Albert; Vliegen, Hubert W.; van der Wall, Ernst E.; Bax, Jeroen J.; Holman, Eduard R.
- Abstract
The aim of this study was to evaluate the feasibility of right ventricular (RV) longitudinal peak systolic strain (LPSS) assessment for the follow-up of adult patients with corrected tetralogy of Fallot (TOF). Adult patients ( n = 18) with corrected TOF underwent echocardiography and CMR twice with a time interval of 4.2 ± 1.7 years. RV performance was derived from CMR, and included RV volumes and ejection fraction (EF). LPSS was calculated globally (GLPSS) and in the RV free wall (LPSS FW), with echocardiographic speckle-tracking strain-analysis. Baseline (G)LPSS values were compared between patients and healthy controls; the relation between (G)LPSS and CMR parameters was evaluated and the changes in (G)LPSS and CMR parameters during follow-up were compared. GLPSS and LPSS FW were significantly reduced in patients as compared to controls (−14.9 ± 0.7% vs. −21.6 ± 0.9% and −15.5 ± 0.9% vs. −22.7 ± 1.5%, P < 0.01). Moderate agreement between LPSS and CMR parameters was observed. RV EF remained unchanged during follow-up, whereas GLPSS and LPSS FW demonstrated a significant reduction. RVEF showed a 1% increase, whereas GLPSS decreased by 14%, and LPSS FW by 27%. RV LPSS is reduced in TOF patients as compared to controls; during follow-up RV EF remained unchanged whereas LPSS decreased suggesting that RV LPSS may be a sensitive marker to detect early deterioration in RV performance.
- Subjects
TETRALOGY of Fallot; CARDIAC contraction; DIAGNOSTIC ultrasonic imaging; ECHOCARDIOGRAPHY; PHYSIOLOGIC strain
- Publication
International Journal of Cardiovascular Imaging, 2009, Vol 25, Issue 7, p669
- ISSN
1569-5794
- Publication type
Article
- DOI
10.1007/s10554-009-9477-7