We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Editorial: O-GlcNAcylation and the immune system.
- Authors
Hart, Gerald W.; Ramakrishnan, Parameswaran
- Abstract
This article explores the role of O-GlcNAcylation in regulating the immune system. O-GlcNAcylation is a post-translational modification that affects cell signaling, metabolism, and development. It has been linked to immune dysfunction and the development of autoimmune, inflammatory, and allergic diseases, as well as immune cell malignancies. The article includes original research articles and comprehensive reviews that cover various aspects of O-GlcNAcylation in the immune system, such as its impact on leukemia, immune cell infiltration, and inflammation. The collection of articles provides a comprehensive overview of O-GlcNAcylation's role in the immune system, highlighting the potential for therapeutic interventions and improved disease diagnoses.
- Subjects
TUMOR-infiltrating immune cells; T-cell exhaustion; MOLECULAR biology; PATHOLOGY; IMMUNOLOGIC diseases; PSYCHONEUROIMMUNOLOGY; AUTOIMMUNE diseases
- Publication
Frontiers in Immunology, 2024, p1
- ISSN
1664-3224
- Publication type
Article
- DOI
10.3389/fimmu.2024.1474042