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- Title
Response to ixekizumab in a patient of psoriasis with secondary failure to secukinumab.
- Authors
Mittal, Saurabh
- Abstract
The patient responded to the therapy with only the nail changes and lesions on the legs persisting. This preliminary pilot therapy showed that low-dose secukinumab intramatricial injection seems to be a quick, effective and safe treatment method for nail psoriasis. Therapy Letter 119 Indian Journal of Dermatology, Venereology and Leprology | Volume 87 | Issue 1 | January-February 2021 right three nails was 62.5%, 75% and 50% for case 1, and showed no significant improvement for case 2. Because the psoriatic nails of case 1 took a turn for the worse, steadily, before treatment, we thought the observed improvement in the untreated nails of case 1 could be attributed to systemic absorption and effects of the drug after low-dose secukinumab injection, especially considering her low body weight.
- Subjects
PSORIATIC arthritis; NAIL diseases; PSORIASIS; RESPIRATORY infections; THERAPEUTIC use of monoclonal antibodies; MONOCLONAL antibodies; DERMATOLOGIC agents
- Publication
Indian Journal of Dermatology, Venereology & Leprology, 2021, Vol 87, Issue 1, p119
- ISSN
0378-6323
- Publication type
case study
- DOI
10.4103/ijdvl.IJDVL_671_19