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- Title
Localization of T-cell subsets in cutaneous lichen planus: An insight into pathogenetic mechanism.
- Authors
Rana, Safia; Gupta, Ruchika; Singh, Sompal; Mohanty, Sandip; Gupta, Kusum; Kudesia, Madhur
- Abstract
The article reports on the results of the evaluation of T cell subsets in cutaneous lichen planus (LP). It states that immunoperoxidase technique was used to determine the immunohistochemistry of T cell helper and T cell suppressor subsets. It notes that LP is a chronic muco-cutaneous inflammatory disease with pathogenetic role of both CD8+ cytotoxic T cells and CD4+ helper T cells. It mentions that majority of the subepithelial and intraepithelial inflammatory cells in oral LP are CD8+ T cells.
- Subjects
LICHEN planus; T cells; IMMUNOENZYME technique; IMMUNOHISTOCHEMISTRY; LYMPHOCYTES
- Publication
Indian Journal of Dermatology, Venereology & Leprology, 2010, Vol 76, Issue 6, p707
- ISSN
0378-6323
- Publication type
Article
- DOI
10.4103/0378-6323.72452