We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Small fiber polyneuropathy as a potential therapeutic target in interstitial cystitis/bladder pain syndrome.
- Authors
Matthews, Catherine A.; Deveshwar, Shaun P.; Evans, Robert J.; Badlani, Gopal; Walker, Stephen J.
- Abstract
Introduction and hypothesis: Interstitial cystitis/bladder pain syndrome (IC/BPS) and fibromyalgia (FM) are frequently co-occurring medical diagnoses in patients referred to the urology clinic for secondary and tertiary treatment options. Methods: Abundant literature has shown that many patients with FM have small fiber polyneuropathy (SFPN) that can be confirmed via skin punch biopsy and immunological staining to measure nerve density. Results and conclusions: This finding of SFPN provides a therapeutic target for FM and in this article we hypothesize and provide rationale for the idea that this same phenomenon (SFPN) might explain, in some IC/BPS patients, the finding of widespread pain and likewise provide a therapeutic target for these patients.
- Subjects
INTERSTITIAL cystitis; DIAGNOSIS; SKIN biopsy; FIBERS
- Publication
International Urogynecology Journal, 2019, Vol 30, Issue 11, p1817
- ISSN
0937-3462
- Publication type
Article
- DOI
10.1007/s00192-019-04011-x