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- Title
Baylis–Hillman adducts with molluscicidal activity against Biomphalaria glabrata.
- Authors
Vasconcellos, Mário L. A. A.; Silva, Tania M. S.; Camara, Celso A.; Martins, Rodrigo M.; Lacerda, Kelly M.; Lopes, Horacimone M.; Pereira, Vera L. P.; de Souza, Rodrigo O. M. A.; Crespo, Lívia T. C.
- Abstract
The molluscicidal activities often Baylis-Hillman adducts against Biomphalaria glabrata (Say) snails, the intermediate host of schistosomiasis, have been determined. Nine of these compounds showed significant molluscicidal activity against B. glabrata, falling below the threshold of 100 μg ml-1 set for potential molluscicidal activity by the World Health Organisation. Among these compounds, 3-hydroxy-2-methylene-3-(4-nitrophenyl)propanenitrile had the highest activity, with LC50 = 6.64 μg ml-1.
- Subjects
EXPERIENTIAL research; BIOMPHALARIA; BIOMPHALARIA glabrata; SNAILS; MOLLUSKS; GASTROPODA; SCHISTOSOMIASIS; ORGANIC compounds; WORLD Health Organization
- Publication
Pest Management Science, 2006, Vol 62, Issue 3, p288
- ISSN
1526-498X
- Publication type
Article
- DOI
10.1002/ps.1153