We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Isoenzymes of alkaline phosphatases in seminomas.
- Authors
Brehmer-Andersson, E.; Ljungdahl-StÅHle, E.; Koshida, K.; Yamamoto, H.; Stigbrand, T.; Wahren, B.
- Abstract
Placental alkaline phosphatase (the PLAP-like isoenzyme) and liver alkaline phosphatase (LAP) were demonstrated immunohistochemically by use of monoclonal antibodies in the tumor cells of twelve seminomas and one seminoma metastasis. Intestinal alkaline phosphatase (IAP) was not found. The PLAP-like and LAP enzymes showed high catalytic activities compared to normal testis. This is the first occasion that LAP has been demonstrated by immunochemistry in seminoma cells. The results suggest that demonstration of these tumor enzymes may be useful markers for seminomas in histopathological specimens.
- Publication
APMIS, 1990, Vol 98, Issue 7-12, p977
- ISSN
0903-4641
- Publication type
Article
- DOI
10.1111/j.1699-0463.1990.tb05023.x