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- Title
Exploring Autophagy in Drosophila.
- Authors
Lőrincz, Péter; Mauvezin, Caroline; Juhász, Gábor
- Abstract
Autophagy is a catabolic process in eukaryotic cells promoting bulk or selective degradation of cellular components within lysosomes. In recent decades, several model systems were utilized to dissect the molecular machinery of autophagy and to identify the impact of this cellular "self-eating" process on various physiological and pathological processes. Here we briefly discuss the advantages and limitations of using the fruit fly Drosophila melanogaster, a popular model in cell and developmental biology, to apprehend the main pathway of autophagy in a complete animal.
- Subjects
AUTOPHAGY; DROSOPHILA melanogaster; LYSOSOMES; DEVELOPMENTAL biology; EUKARYOTIC cells; PHYSIOLOGY
- Publication
Cells (2073-4409), 2017, Vol 6, Issue 3, p22
- ISSN
2073-4409
- Publication type
Article
- DOI
10.3390/cells6030022