We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Copper Catalyzed Inverse Electron Demand [4+2] Cycloaddition for the Synthesis of Oxazines.
- Authors
Yang, Weiguang; Zhou, Zitong; Zhao, Yu; Luo, Danyang; Luo, Xiai; Luo, Hui; Cui, Liao; Li, Li
- Abstract
A copper catalyzed tandem CuAAC/ring cleavage/[4+2] annulation reaction of terminal ynones, sulfonyl azides, and imines has been developed to synthesize the functionalized oxazines under mild conditions. Particularly, the intermediate N-sulfonyl acylketenimines undergo cycloaddition of an inverse electron demand Diels–Alder reaction with imines and a series of 1,3-oxazine derivatives were obtained successfully in good yields.
- Subjects
RING formation (Chemistry); OXAZINES; DIELS-Alder reaction; COPPER; ELECTRONS; SULFONYL azides; ANNULATION
- Publication
Catalysts (2073-4344), 2022, Vol 12, Issue 5, p526
- ISSN
2073-4344
- Publication type
Article
- DOI
10.3390/catal12050526