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- Title
Risk analysis of depression among adult patients with epilepsy of different sex: a retrospective single-center study from China.
- Authors
Wang Guo; Yu-xuan Li; Yi Zhang; Xue-rui Lv; Sheng-xue Wang; Shuang-yuan Zhang; En-si Wang; Xin-jie Chen; Yun Li
- Abstract
Objective: To determine sex differences in the prevalence of depression and assess the risk factors for depression among adult patients with epilepsy from the Dali area of China. Methods: We retrospectively analyzed the clinical data of adult patients with epilepsy who visited the First Affiliated Hospital of Dali University from January 2017 to January 2022. Patient Health Questionnaire-9 was used to assess depressive symptoms in patients with epilepsy. The risk factors of depression were analyzed by binary logistic regression among different sex in patients with epilepsy. Results: There were significant sex differences in depression in patients with epilepsy (p<0.001), and females were 4.27 times more likely to suffer from depression than males (95% confidence interval: 3.70-4.92). The risk factors for depression among female patients with epilepsy included occupation (p<0.001), years with epilepsy (p<0.001), seizure frequency (p<0.001), seizure type (p<0.001), etiology (p<0.001), number of antiseizure medications used (p< 0.001), antiseizure medications (p<0.001), and electroencephalogram findings (p<0.001). The risk factors for depression among male patients with epilepsy included age (p<0.001), ethnicity (p<0.001), occupation (p<0.001), years with epilepsy (p<0.001), seizure frequency (p<0.001), seizure type (p<0.001), etiology (p<0.001), number of antiseizure medications used (p<0.001), antiseizure medications (p<0.001), and electroencephalogram findings (p<0.001). Conclusion: Adult female patients with epilepsy had a higher risk of depression than adult male patients with epilepsy. There were sex differences in the risk factors associated with depression among patients with epilepsy.
- Subjects
CHINA; SEX factors in disease; PEOPLE with epilepsy; RISK assessment; DEPRESSION in men; DEPRESSION in women
- Publication
Frontiers in Psychiatry, 2023, p1
- ISSN
1664-0640
- Publication type
Article
- DOI
10.3389/fpsyt.2023.1283983