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- Title
Antibacterial activity of stannate M<sub>2</sub>SnO<sub>4</sub> (M = Co, Cu, Mg, Ni and Zn) nanoparticles prepared by hydrothermal.
- Authors
Alghamdi, Azzah Ibrahim; Ababutain, Ibtisam Mohammed; Alonizan, Nora Hamad; Hjiri, Mokhtar; Hammad, Ahmed Hosny; Zerrad, B.; Aida, Mohammed Salah
- Abstract
In the present work, stannate nanoparticles M2SnO4(M = Co, Cu, Mg, Ni and Zn) were synthetized using hydrothermal technique. The structural and morphological properties of the synthetized nanoparticles have been analyzed by means of X-ray diffraction (XRD) and high-resolution transmission microscopy (HRTEM). The antibacterial activity of these stannate has been investigated using the agar well diffusion technique. The structural analysis results reveal the monocrystalline nature of the prepared nanoparticles and the presence of SnO2 as secondary phase beside a small amount of metallic oxide. The antibacterial activity of the synthetized stannate nanoparticles was tested against a Gram-negative and Gram-positive bacteria. The results showed that all stannate nanoparticles except Mg stannate exhibit an activation against both Gram-positive and Gram-negative bacteria. The Cu and Zn stannate demonstrated higher antibacterial activity by comparison to the other stannate suggesting their potential candidature for the antibacterial activity and their utilization to develop a new antibacterial agent. A correlation between the antibacterial activity and the nanoparticle crystallite size is addressed. We concluded that a crystallite size of 12 nm seems to be an optimal size for efficient antibacterial activity of the stannate nanoparticles.
- Subjects
ANTIBACTERIAL agents; NANOPARTICLE size; NANOPARTICLES; METALLIC oxides; GRAM-negative bacteria; COPPER-zinc alloys; SILVER nanoparticles
- Publication
Applied Nanoscience, 2022, Vol 12, Issue 5, p1601
- ISSN
2190-5509
- Publication type
Article
- DOI
10.1007/s13204-021-02274-9