Back to matchesWe found a matchYour institution may have rights to this item. Sign in to continue.TitleLoss of p53 and centrosome hyperamplification.AuthorsTarapore, Pheruza; Fukasawa, KenjiAbstractDiscusses the molecular aspects of how loss or mutational inactivation of p53 leads to centrosome hyperamplification. Function of p53 tumor suppressor gene; Causes of centrosome amplification; Background on the p53 inactivation in human cancer.SubjectsP53 antioncogene; CENTROSOMES; ONCOGENES; CANCERPublicationOncogene, 2002, Vol 21, Issue 40, p6234ISSN0950-9232Publication typeArticleDOI10.1038/sj.onc.1205707