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Liquid biopsy, a paradigm shift in oncology: what interventional radiologists should know.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Loss of AXIN1 drives acquired resistance to WNT pathway blockade in colorectal cancer cells carrying RSPO3 fusions.
- Published in:
- EMBO Molecular Medicine, 2017, v. 9, n. 3, p. 293, doi. 10.15252/emmm.201606773
- By:
- Publication type:
- Article
Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Liquid Biopsies for Monitoring Temporal Genomic Heterogeneity in Breast and Colon Cancers.
- Published in:
- Pathobiology, 2018, v. 85, n. 1/2, p. 146, doi. 10.1159/000473882
- By:
- Publication type:
- Article
Toward understanding and exploiting tumor heterogeneity.
- Published in:
- Nature Medicine, 2015, v. 21, n. 8, p. 846, doi. 10.1038/nm.3915
- By:
- Publication type:
- Article
The road to resistance: EGFR mutation and cetuximab.
- Published in:
- Nature Medicine, 2012, v. 18, n. 2, p. 199, doi. 10.1038/nm.2646
- By:
- Publication type:
- Article
Somatic alterations as the basis for resistance to targeted therapies.
- Published in:
- Journal of Pathology, 2014, v. 232, n. 2, p. 244, doi. 10.1002/path.4278
- By:
- Publication type:
- Article
Broccoli, PTEN deletion and prostate cancer: where is the link?
- Published in:
- Molecular Cancer, 2010, v. 9, p. 308, doi. 10.1186/1476-4598-9-308
- By:
- Publication type:
- Article
Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46685-y
- By:
- Publication type:
- Article
Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer.
- Published in:
- Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-023-01275-3
- By:
- Publication type:
- Article
Activation of β-Catenin by Oncogenic PIK3CA and EGFR Promotes Resistance to Glucose Deprivation by Inducing a Strong Antioxidant Response.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037526
- By:
- Publication type:
- Article
Active PI3K Pathway Causes an Invasive Phenotype Which Can Be Reversed or Promoted by Blocking the Pathway at Divergent Nodes.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036402
- By:
- Publication type:
- Article
KRAS Mutations Testing in Colorectal Carcinoma Patients in Italy: From Guidelines to External Quality Assessment.
- Published in:
- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029146
- By:
- Publication type:
- Article
Mutational Profiling of Kinases in Human Tumours of Pancreatic Origin Identifies Candidate Cancer Genes in Ductal and Ampulla of Vater Carcinomas.
- Published in:
- PLoS ONE, 2010, v. 5, n. 9, p. 1, doi. 10.1371/journal.pone.0012653
- By:
- Publication type:
- Article
Multi-Determinants Analysis of Molecular Alterations for Predicting Clinical Benefit to EGFR-Targeted Monoclonal Antibodies in Colorectal Cancer.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007287
- By:
- Publication type:
- Article
Mutational Profile of GNAQ<sup>Q209</sup> in Human Tumors.
- Published in:
- PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006833
- By:
- Publication type:
- Article
Absence of AKT1 Mutations in Glioblastoma.
- Published in:
- PLoS ONE, 2009, v. 4, n. 5, p. 1, doi. 10.1371/journal.pone.0005638
- By:
- Publication type:
- Article
Inhibition of Heme Export and/or Heme Synthesis Potentiates Metformin Anti-Proliferative Effect on Cancer Cell Lines.
- Published in:
- Cancers, 2022, v. 14, n. 5, p. 1230, doi. 10.3390/cancers14051230
- By:
- Publication type:
- Article
Efficacy of Retreatment with Oxaliplatin-Based Regimens in Metastatic Colorectal Cancer Patients: The RETROX-CRC Retrospective Study.
- Published in:
- Cancers, 2022, v. 14, n. 5, p. 1197, doi. 10.3390/cancers14051197
- By:
- Publication type:
- Article
Delta-Radiomics Predicts Response to First-Line Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients with Liver Metastases.
- Published in:
- Cancers, 2022, v. 14, n. 1, p. 241, doi. 10.3390/cancers14010241
- By:
- Publication type:
- Article
PARP1 Inhibitor and Trabectedin Combination Does Not Increase Tumor Mutational Burden in Advanced Sarcomas—A Preclinical and Translational Study.
- Published in:
- Cancers, 2021, v. 13, n. 24, p. 6295, doi. 10.3390/cancers13246295
- By:
- Publication type:
- Article
Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways.
- Published in:
- Cancers, 2021, v. 13, n. 15, p. 3805, doi. 10.3390/cancers13153805
- By:
- Publication type:
- Article
Mechanisms of Immune Escape and Resistance to Checkpoint Inhibitor Therapies in Mismatch Repair Deficient Metastatic Colorectal Cancers.
- Published in:
- Cancers, 2021, v. 13, n. 11, p. 2638, doi. 10.3390/cancers13112638
- By:
- Publication type:
- Article
Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer.
- Published in:
- Cancers, 2020, v. 12, n. 3, p. 685, doi. 10.3390/cancers12030685
- By:
- Publication type:
- Article
Preclinical efficacy of carfilzomib in BRAF‐mutant colorectal cancer models.
- Published in:
- Molecular Oncology, 2024, v. 18, n. 6, p. 1552, doi. 10.1002/1878-0261.13595
- By:
- Publication type:
- Article
Transcriptome‐wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer.
- Published in:
- Molecular Oncology, 2024, v. 18, n. 6, p. 1460, doi. 10.1002/1878-0261.13622
- By:
- Publication type:
- Article
Dual VEGFA/BRAF targeting boosts PD‐1 blockade in melanoma through GM‐CSF‐mediated infiltration of M1 macrophages.
- Published in:
- Molecular Oncology, 2023, v. 17, n. 8, p. 1474, doi. 10.1002/1878-0261.13450
- By:
- Publication type:
- Article
Towards a cancer mission in Horizon Europe: recommendations.
- Published in:
- Molecular Oncology, 2020, v. 14, n. 8, p. 1589, doi. 10.1002/1878-0261.12763
- By:
- Publication type:
- Article
Exploiting DNA repair defects in colorectal cancer.
- Published in:
- Molecular Oncology, 2019, v. 13, n. 4, p. 681, doi. 10.1002/1878-0261.12467
- By:
- Publication type:
- Article
Early‐onset colorectal cancer in young individuals.
- Published in:
- Molecular Oncology, 2019, v. 13, n. 2, p. 109, doi. 10.1002/1878-0261.12417
- By:
- Publication type:
- Article
Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition.
- Published in:
- NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00706-7
- By:
- Publication type:
- Article
Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists.
- Published in:
- Oncogene, 1999, v. 18, n. 37, p. 5221, doi. 10.1038/sj.onc.1202899
- By:
- Publication type:
- Article
Loss of the exon encoding the juxtamembrane domain is essential for the oncogenic activation of TPR-MET.
- Published in:
- Oncogene, 1999, v. 18, n. 29, p. 4275, doi. 10.1038/sj.onc.1202791
- By:
- Publication type:
- Article
Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis.
- Published in:
- Oncogene, 1999, v. 18, n. 5, p. 1139, doi. 10.1038/sj.onc.1202607
- By:
- Publication type:
- Article
Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.
- Published in:
- Oncogene, 1997, v. 15, n. 25, p. 3103, doi. 10.1038/sj.onc.1201561
- By:
- Publication type:
- Article
Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
- Published in:
- Oncogene, 1997, v. 14, n. 6, p. 705, doi. 10.1038/sj.onc.1200879
- By:
- Publication type:
- Article
The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.
- Published in:
- Neuro-Oncology, 2014, v. 16, n. 9, p. 1263, doi. 10.1093/neuonc/nou005
- By:
- Publication type:
- Article
The analysis of PIK3CA mutations in gastric carcinoma and metanalysis of literature suggest that exon-selectivity is a signature of cancer type.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2010, v. 29, p. 32, doi. 10.1186/1756-9966-29-32
- By:
- Publication type:
- Article
Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
- Published in:
- FASEB Journal, 2015, v. 29, n. 2, p. 464, doi. 10.1096/fj.14-262303
- By:
- Publication type:
- Article
Mutational signatures of colorectal cancers according to distinct computational workflows.
- Published in:
- Briefings in Bioinformatics, 2024, v. 25, n. 4, p. 1, doi. 10.1093/bib/bbae249
- By:
- Publication type:
- Article
Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family.
- Published in:
- International Journal of Cancer, 1999, v. 82, n. 5, p. 640, doi. 10.1002/(SICI)1097-0215(19990827)82:5<640::AID-IJC4>3.0.CO;2-6
- By:
- Publication type:
- Article
Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance.
- Published in:
- Nature Communications, 2017, v. 8, n. 6, p. 1, doi. 10.1038/ncomms15617
- By:
- Publication type:
- Article
Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers.
- Published in:
- Nature Communications, 2015, v. 6, n. 9, p. 8305, doi. 10.1038/ncomms9305
- By:
- Publication type:
- Article
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
- Published in:
- Nature Communications, 2015, v. 6, n. 4, p. 7002, doi. 10.1038/ncomms8002
- By:
- Publication type:
- Article
High-dose vitamin C enhances cancer immunotherapy.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 532, p. 1, doi. 10.1126/scitranslmed.aay8707
- By:
- Publication type:
- Article
MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations.
- Published in:
- Science Translational Medicine, 2016, v. 8, n. 324, p. 1, doi. 10.1126/scitranslmed.aad5640
- By:
- Publication type:
- Article
Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance.
- Published in:
- Genome Biology, 2014, v. 15, n. 8, p. 449, doi. 10.1186/s13059-014-0449-4
- By:
- Publication type:
- Article
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Parallel Evaluation of Circulating Tumor DNA and Circulating Tumor Cells in Metastatic Colorectal Cancer.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Colorectal cancer: Mutations in a signalling pathway.
- Published in:
- Nature, 2005, v. 436, n. 7052, p. 792, doi. 10.1038/436792a
- By:
- Publication type:
- Article