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- Title
Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis.
- Authors
Walsh, David A.; McWilliams, Dan F.; Turley, Matthew J.; Dixon, Madeleine R.; Fransès, Rebecca E.; Mapp, Paul I.; Wilson, Deborah
- Abstract
Objectives. The osteochondral junction can be a source of pain in both RA and OA. Growth of blood vessels and nerves from the subchondral bone into articular cartilage may mediate the association between joint pathology and symptoms. We have investigated associations between angiogenesis, inflammation and neurovascular growth factor expression at the osteochondral junction in human arthritis.
- Subjects
OSTEOCHONDROSIS; RHEUMATOID arthritis; OSTEOARTHRITIS; BLOOD-vessel development; BONE diseases; ARTICULAR cartilage diseases
- Publication
Rheumatology, 2010, Vol 49, Issue 10, p1852
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/keq188